Jennifer A. Maynard, Ph.D.

Affiliations: 
2001 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
discovery and development of protein therapeutics and applied immunology by capitalizing on state of the art protein engineering, directed evolution and systems biology technologies
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"Jennifer Maynard"
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Parents

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George Georgiou grad student 2001 UT Austin
 (Engineering antibody therapeutics: Approaches to neutralizing bacterial toxins.)
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Publications

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Siles N, Schuler M, Maguire C, et al. (2023) SARS-CoV-2 Humoral Immune Responses in Convalescent Individuals Over 12 Months Reveal Severity-Dependent Antibody Dynamics. Medrxiv : the Preprint Server For Health Sciences
Maynard JA, Segatori L. (2023) Editorial overview: Tissue, cell, and pathway engineering: Recent innovations in biomedical technologies. Current Opinion in Biotechnology. 83: 102981
Silva RP, Huang Y, Nguyen AW, et al. (2023) Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses. Elife. 12
Qerqez AN, Silva RP, Maynard JA. (2023) Outsmarting Pathogens with Antibody Engineering. Annual Review of Chemical and Biomolecular Engineering
Bowen JE, Park YJ, Stewart C, et al. (2022) SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines. Science Immunology. eadf1421
Liu Y, Nguyen AW, Maynard JA. (2022) Engineering antibodies for conditional activity in the solid tumor microenvironment. Current Opinion in Biotechnology. 78: 102809
Goldsmith JA, DiVenere AM, Maynard JA, et al. (2022) Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin. Cell Reports. 40: 111196
DiVenere AM, Amengor D, Silva RP, et al. (2022) Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis. Mbio. e0152722
Liu Y, Lee AG, Nguyen AW, et al. (2022) An antibody Fc engineered for conditional antibody-dependent cellular cytotoxicity at the low tumor microenvironment pH using mammalian cell display. The Journal of Biological Chemistry. 101798
Costello SM, Shoemaker SR, Hobbs HT, et al. (2022) The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes. Nature Structural & Molecular Biology
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