Diem-Thu T. Lesher, Ph.D.

Affiliations: 
2004 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Structural Studies of Dynamic Cellular Processes
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Matthew R. Redinbo grad student 2004 UNC Chapel Hill
 (Structural analyses of human topoisomerase I and Escherichia coli TraI: Understanding DNA relaxation and conjugation.)
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Publications

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Antony S, Theruvathu JA, Brooks PJ, et al. (2004) Enhancement of camptothecin-induced topoisomerase I cleavage complexes by the acetaldehyde adduct N2-ethyl-2'-deoxyguanosine. Nucleic Acids Research. 32: 5685-92
Lesher DT, Pommier Y, Stewart L, et al. (2002) 8-Oxoguanine rearranges the active site of human topoisomerase I. Proceedings of the National Academy of Sciences of the United States of America. 99: 12102-7
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