Sean R. Marcsisin, Ph.D.
Affiliations: | 2011 | Chemistry | Northeastern University, Boston, MA, United States |
Area:
Bioanalytical chemistry, mass spectrometry, hydrogen/deuterium exchangeGoogle:
"Sean Marcsisin"Mean distance: 10.98 | S | N | B | C | P |
Parents
Sign in to add mentor| John R. Engen | grad student | 2011 | Northeastern University | |
| (Towards a More Complete Conformational Understanding of the HIV-1 Viral Infectivity Factor.) | ||||
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Publications
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| Kancharla P, Dodean RA, Li Y, et al. (2020) Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials. Journal of Medicinal Chemistry |
| Dodean RA, Kancharla P, Li Y, et al. (2019) Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. Journal of Medicinal Chemistry |
| Chaikuad A, Filippakopoulos P, Marcsisin SR, et al. (2017) Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly. Structure (London, England : 1993) |
| Milner EE, Berman J, Caridha D, et al. (2016) Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei. Malaria Journal. 15: 588 |
| Jin X, Potter B, Luong TL, et al. (2016) Pre-clinical evaluation of CYP 2D6 dependent drug-drug interactions between primaquine and SSRI/SNRI antidepressants. Malaria Journal. 15: 280 |
| Marcsisin SR, Reichard G, Pybus BS. (2016) Primaquine pharmacology in the context of CYP 2D6 pharmacogenomics: Current state of the art. Pharmacology & Therapeutics |
| Marcsisin SR, Liptak C, Marineau J, et al. (2015) Tag and Capture Flow Hydrogen Exchange Mass Spectrometry with a Fluorous-Immobilized Probe. Analytical Chemistry. 87: 6349-56 |
| Vuong C, Xie LH, Potter BM, et al. (2015) Differential Cytochrome P450 2D Metabolism Alters Tafenoquine Pharmacokinetics. Antimicrobial Agents and Chemotherapy. 59: 3864-9 |
| Potter BM, Xie LH, Vuong C, et al. (2015) Differential CYP 2D6 metabolism alters primaquine pharmacokinetics. Antimicrobial Agents and Chemotherapy. 59: 2380-7 |
| Fasinu PS, Tekwani BL, Nanayakkara NP, et al. (2014) Enantioselective metabolism of primaquine by human CYP2D6. Malaria Journal. 13: 507 |