Jason Tien, Ph.D.

Affiliations: 
2014 Neuroscience University of California, San Francisco, San Francisco, CA 
Area:
Channel Physiology
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"Jason Tien"
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SNBCP

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Lily Y. Jan grad student 2014 UCSF
 (Studies ofTMEM16A Calcium Activated Chloride Channel Structure and Function.)
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Publications

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Wang TA, Chen C, Huang F, et al. (2021) TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures. Proceedings of the National Academy of Sciences of the United States of America. 118
Peters CJ, Gilchrist JM, Tien J, et al. (2018) The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel. Neuron
Dang S, Feng S, Tien J, et al. (2017) Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature
Zhang Y, Zhang Z, Xiao S, et al. (2017) Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning. Neuron. 95: 1103-1111.e4
Peters CJ, Chen T, Tien J, et al. (2017) Identification of Critical Residues for Anion Conductance in the TMEM16A Channel Biophysical Journal. 112: 173a
Peters CJ, Yu H, Tien J, et al. (2015) Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels. Proceedings of the National Academy of Sciences of the United States of America. 112: 3547-52
Tien J, Peters CJ, Wong XM, et al. (2014) A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. 3
Tien J, Peters CJ, Wong XM, et al. (2014) Author response: A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity Elife
Tien J, Young DM, Jan YN, et al. (2014) Molecular Properties of Ion Channels From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience: Third Edition. 323-348
Tien J, Lee HY, Minor DL, et al. (2013) Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proceedings of the National Academy of Sciences of the United States of America. 110: 6352-7
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