Taryn E. Grieder, Ph.D.

Affiliations: 
2012 Medical Science University of Toronto, Toronto, ON, Canada 
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Derek van der Kooy grad student 2012 University of Toronto
 (The Involvement of Ventral Tegmental Area Dopamine and CRF Activity in Mediating the Opponent Motivational Effects of Acute and Chronic Nicotine.)
Olivier George post-doc 2014- Scripps Institute
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Publications

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Vargas-Perez H, Grieder TE, van der Kooy D. (2022) Neural Plasticity in the Ventral Tegmental Area, Aversive Motivation during Drug Withdrawal and Hallucinogenic Therapy. Journal of Psychoactive Drugs. 1-11
Grieder TE, Yee M, Vargas-Perez H, et al. (2021) Administration of BDNF in the ventral tegmental area produces a switch from a nicotine-non-dependent D1R-mediated motivational state to a nicotine-dependent-like D2R-mediated motivational state. The European Journal of Neuroscience
Yee M, Maal-Bared G, Ting-A-Kee R, et al. (2020) Segregation of caffeine reward and aversion in the rat nucleus accumbens shell versus core. The European Journal of Neuroscience
Grieder TE, Besson M, Maal-Bared G, et al. (2019) β2* nAChRs on VTA dopamine and GABA neurons separately mediate nicotine aversion and reward. Proceedings of the National Academy of Sciences of the United States of America
Grieder TE, George O, Yee M, et al. (2017) Deletion of α5 nicotine receptor subunits abolishes nicotinic aversive motivational effects in a manner that phenocopies dopamine receptor antagonism. The European Journal of Neuroscience
Vargas-Perez H, Grieder TE, Ting-A-Kee R, et al. (2017) A single administration of the hallucinogen, 4-acetoxy-dimethyltryptamine, prevents the shift to a drug-dependent state and the expression of withdrawal aversions in rodents. The European Journal of Neuroscience
Grieder TE, Herman MA, Contet C, et al. (2014) VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation. Nature Neuroscience. 17: 1751-8
Grieder TE, George O, Tan H, et al. (2012) Phasic D1 and tonic D2 dopamine receptor signaling double dissociate the motivational effects of acute nicotine and chronic nicotine withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 109: 3101-6
George O, Grieder TE, Cole M, et al. (2010) Exposure to chronic intermittent nicotine vapor induces nicotine dependence. Pharmacology, Biochemistry, and Behavior. 96: 104-7
Grieder TE, Sellings LH, Vargas-Perez H, et al. (2010) Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 943-54
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