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Erwan Bezard

Affiliations: 
Université de Bordeaux, Talence, Nouvelle-Aquitaine, France 
Area:
neurodegenerative disorders
Website:
http://www.inb.u-bordeaux2.fr/dev/FR/equipe.php?equipe=Physiopathologie%20des%20syndromes%20parkinsoniens
Google:
"Erwan Bezard"
Bio:

Bezard has authored or co-authored over 90 professional publications in the field of neurobiology, most of which are on Parkinson's disease and related disorders. He is perhaps best known for the reappraisal of both the identification of the nature of compensatory mechanisms that mask the progression Parkinson's disease and their sequential activation in non-human primate models that mimic Parkinson’s progression. His current research interests include the study of the compensatory mechanisms, the levodopa-induced dyskinesia, the basic pathophysiology of basal ganglia circuitry, and the development of new strategies to alleviate symptoms and/or to slow disease progression.

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Mean distance: 15.8 (cluster 6)
 		SNBCP
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Parents

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Bernard H. Bioulac grad student 1995-1998 Université de Bordeaux
Christian E. Gross grad student 1995-1998 Université de Bordeaux
 (PhD thesis)
Jonathan M. Brotchie post-doc 1999-2000 The University of Manchester
Alan R. Crossman post-doc 1999-2000 The University of Manchester

Children

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Sandra Dovero grad student Université de Bordeaux
Michel Engeln grad student 2010-2013 Université de Bordeaux
Mathieu Bourdenx grad student 2012-2015 Université de Bordeaux
Salvatore Novello grad student 2014-2019 Université de Bordeaux

Collaborators

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BETA: Related publications

Publications

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Darricau M, Katsinelos T, Raschella F, et al. (2022) Tau seeds from patients induce progressive supranuclear palsy pathology and symptoms in primates. Brain : a Journal of Neurology
Teil M, Doudnikoff E, Thiolat ML, et al. (2022) The Zinc Ionophore Clioquinol Reduces Parkinson's Disease Patient-Derived Brain Extracts-Induced Neurodegeneration. Molecular Neurobiology
Arotcarena ML, Soria FN, Cunha A, et al. (2022) Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function. Aging Cell. 21: e13584
Teil M, Dovero S, Bourdenx M, et al. (2022) Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology. Brain : a Journal of Neurology
Bezard E, Dehay B. (2022) [Aggregation and spread of synuclein in Parkinson's disease]. Medecine Sciences : M/S. 38: 45-51
Laferrière F, Claverol S, Bezard E, et al. (2022) Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson's disease. Npj Parkinson's Disease. 8: 10
Novello S, Mercatelli D, Albanese F, et al. (2022) In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity. Neurobiology of Disease. 162: 105579
Blesa J, Foffani G, Dehay B, et al. (2021) Motor and non-motor circuit disturbances in early Parkinson disease: which happens first? Nature Reviews. Neuroscience
Arotcarena ML, Dovero S, Biendon N, et al. (2021) Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques. Frontiers in Bioengineering and Biotechnology. 9: 762209
Malave L, Zuelke DR, Uribe-Cano S, et al. (2021) Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesia. Communications Biology. 4: 1071
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