Erwan Bezard

Université de Bordeaux, Talence, Nouvelle-Aquitaine, France 
neurodegenerative disorders
"Erwan Bezard"

Bezard has authored or co-authored over 90 professional publications in the field of neurobiology, most of which are on Parkinson's disease and related disorders. He is perhaps best known for the reappraisal of both the identification of the nature of compensatory mechanisms that mask the progression Parkinson's disease and their sequential activation in non-human primate models that mimic Parkinson’s progression. His current research interests include the study of the compensatory mechanisms, the levodopa-induced dyskinesia, the basic pathophysiology of basal ganglia circuitry, and the development of new strategies to alleviate symptoms and/or to slow disease progression.

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Mean distance: 15.8 (cluster 6)
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Laferrière F, Claverol S, Bezard E, et al. (2022) Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson's disease. Npj Parkinson's Disease. 8: 10
Novello S, Mercatelli D, Albanese F, et al. (2022) In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity. Neurobiology of Disease. 162: 105579
Blesa J, Foffani G, Dehay B, et al. (2021) Motor and non-motor circuit disturbances in early Parkinson disease: which happens first? Nature Reviews. Neuroscience
Arotcarena ML, Dovero S, Biendon N, et al. (2021) Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques. Frontiers in Bioengineering and Biotechnology. 9: 762209
Malave L, Zuelke DR, Uribe-Cano S, et al. (2021) Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesia. Communications Biology. 4: 1071
Becker G, Michel A, Bahri MA, et al. (2021) Monitoring of a progressive functional dopaminergic deficit in the A53T-AAV synuclein rats by combining 6-[F]fluoro-L-m-tyrosine imaging and motor performances analysis. Neurobiology of Aging. 107: 142-152
Bassil F, Delamarre A, Canron MH, et al. (2021) Impaired brain insulin signalling in Parkinson's disease. Neuropathology and Applied Neurobiology
Darricau M, Canron MH, Bosc M, et al. (2021) Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment. Neurobiology of Aging. 107: 53-56
Hagenow S, Affini A, Pioli EY, et al. (2021) Adenosine AR/AR Antagonists Enabling Additional HR Antagonism for the Treatment of Parkinson's Disease. Journal of Medicinal Chemistry
Sun X, Yu X, Zhang L, et al. (2021) Comparison of the expression and toxicity of AAV2/9 carrying the human A53T α-synuclein gene in presence or absence of WPRE. Heliyon. 7: e06302
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