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Philippe Sarret, PhD

Affiliations: 
Physiology and Biophysics Université de Sherbrooke, Sherbrooke, Québec, Canada 
Area:
Pain, Neurotensin receptors, Neurophysiology
Website:
http://sarretpainlab.com
Google:
"Philippe Sarret"
Mean distance: 17.91 (cluster 11)
 
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Publications

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Girard M, Bellefeuille SD, Eiselt É, et al. (2023) Ligand-dependent intracellular trafficking of the G protein-coupled P2Y receptor. Biochimica Et Biophysica Acta. Molecular Cell Research. 1870: 119476
Previti S, Desgagné M, Tourwé D, et al. (2022) Opening the amino acid toolbox for peptide-based NTS2-selective ligands as promising lead compounds for pain management. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3471
Tran K, Sainsily X, Côté J, et al. (2022) Size-Reduced Macrocyclic Analogues of [Pyr]-apelin-13 Showing Negative Gα Bias Still Produce Prolonged Cardiac Effects. Journal of Medicinal Chemistry. 65: 531-551
Chartier M, Desgagné M, Sousbie M, et al. (2021) Pharmacodynamic and pharmacokinetic profiles of a neurotensin receptor type 2 (NTS2) analgesic macrocyclic analog. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 141: 111861
Michaelian N, Sadybekov A, Besserer-Offroy É, et al. (2021) Structural insights on ligand recognition at the human leukotriene B4 receptor 1. Nature Communications. 12: 2971
Vivancos M, Fanelli R, Besserer-Offroy É, et al. (2021) Metabolically Stable Neurotensin Analogs Exert Potent and Long-Acting Analgesia Without Hypothermia. Behavioural Brain Research. 113189
Chartier M, Desgagné M, Sousbie M, et al. (2021) Design, Structural Optimization, and Characterization of the First Selective Macrocyclic Neurotensin Receptor Type 2 Non-opioid Analgesic. Journal of Medicinal Chemistry
Besserer-Offroy É, Brouillette RL, Longpré JM, et al. (2020) Assessing Gα-signaling with IP-One: Single Plate Transfection and Assay Protocol for Cell-Based High-Throughput Assay. Bio-Protocol. 10: e3715
Trân K, Murza A, Sainsily X, et al. (2020) Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor. Journal of Medicinal Chemistry
Sadybekov AA, Brouillette RL, Marin E, et al. (2020) Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR. Biomolecules. 10
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