| Year |
Citation |
Score |
| 2024 |
Breault É, Desgagné M, Neve J, Côté J, Barlow TMA, Ballet S, Sarret P. Multitarget Ligands that Comprise Opioid/Nonopioid Pharmacophores for Pain Management: Current State of the Science. Pharmacological Research. 107408. PMID 39307212 DOI: 10.1016/j.phrs.2024.107408 |
0.339 |
|
| 2024 |
Desgagné M, Chartier M, Lagard C, Ferková S, Choquette M, Longpré JM, Côté J, Boudreault PL, Sarret P. Development of Macrocyclic Neurotensin Receptor Type 2 (NTS2) Opioid-Free Analgesics. Angewandte Chemie (International Ed. in English). e202405941. PMID 39110923 DOI: 10.1002/anie.202405941 |
0.342 |
|
| 2024 |
Midavaine É, Brouillette RL, Théberge E, Mona CE, Kashem SW, Côté J, Zeugin V, Besserer-Offroy É, Longpré JM, Marsault É, Sarret P. Discovery of a CCR2-targeting pepducin therapy for chronic pain. Pharmacological Research. 107242. PMID 38823470 DOI: 10.1016/j.phrs.2024.107242 |
0.75 |
|
| 2022 |
Previti S, Desgagné M, Tourwé D, Cavelier F, Sarret P, Ballet S. Opening the amino acid toolbox for peptide-based NTS2-selective ligands as promising lead compounds for pain management. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3471. PMID 36539999 DOI: 10.1002/psc.3471 |
0.382 |
|
| 2022 |
Tran K, Sainsily X, Côté J, Coquerel D, Couvineau P, Saibi S, Haroune L, Besserer-Offroy É, Flynn-Robitaille J, Resua Rojas M, Murza A, Longpré JM, Auger-Messier M, Lesur O, Bouvier M, ... ... Sarret P, et al. Size-Reduced Macrocyclic Analogues of [Pyr]-apelin-13 Showing Negative Gα Bias Still Produce Prolonged Cardiac Effects. Journal of Medicinal Chemistry. 65: 531-551. PMID 34982553 DOI: 10.1021/acs.jmedchem.1c01708 |
0.693 |
|
| 2021 |
Chartier M, Desgagné M, Sousbie M, Rumsby C, Chevillard L, Théroux L, Haroune L, Côté J, Longpré JM, Boudreault PL, Marsault É, Sarret P. Pharmacodynamic and pharmacokinetic profiles of a neurotensin receptor type 2 (NTS2) analgesic macrocyclic analog. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 141: 111861. PMID 34229249 DOI: 10.1016/j.biopha.2021.111861 |
0.371 |
|
| 2021 |
Michaelian N, Sadybekov A, Besserer-Offroy É, Han GW, Krishnamurthy H, Zamlynny BA, Fradera X, Siliphaivanh P, Presland J, Spencer KB, Soisson SM, Popov P, Sarret P, Katritch V, Cherezov V. Structural insights on ligand recognition at the human leukotriene B4 receptor 1. Nature Communications. 12: 2971. PMID 34016973 DOI: 10.1038/s41467-021-23149-1 |
0.713 |
|
| 2021 |
Vivancos M, Fanelli R, Besserer-Offroy É, Beaulieu S, Chartier M, Resua-Rojas M, Mona CE, Previti S, Rémond E, Longpré JM, Cavelier F, Sarret P. Metabolically Stable Neurotensin Analogs Exert Potent and Long-Acting Analgesia Without Hypothermia. Behavioural Brain Research. 113189. PMID 33607165 DOI: 10.1016/j.bbr.2021.113189 |
0.769 |
|
| 2021 |
Chartier M, Desgagné M, Sousbie M, Côté J, Longpré JM, Marsault E, Sarret P. Design, Structural Optimization, and Characterization of the First Selective Macrocyclic Neurotensin Receptor Type 2 Non-opioid Analgesic. Journal of Medicinal Chemistry. PMID 33538583 DOI: 10.1021/acs.jmedchem.0c01726 |
0.359 |
|
| 2020 |
Besserer-Offroy É, Brouillette RL, Longpré JM, Sarret P. Assessing Gα-signaling with IP-One: Single Plate Transfection and Assay Protocol for Cell-Based High-Throughput Assay. Bio-Protocol. 10: e3715. PMID 33659379 DOI: 10.21769/BioProtoc.3715 |
0.696 |
|
| 2020 |
Sadybekov AA, Brouillette RL, Marin E, Sadybekov AV, Luginina A, Gusach A, Mishin A, Besserer-Offroy É, Longpré JM, Borshchevskiy V, Cherezov V, Sarret P, Katritch V. Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR. Biomolecules. 10. PMID 33287369 DOI: 10.3390/biom10121634 |
0.723 |
|
| 2020 |
Gonzalez S, Dumitrascuta M, Eiselt E, Louis S, Kunze L, Blasiol A, Vivancos M, Previti S, Dewolf E, Martin C, Tourwè D, Cavelier F, Gendron L, Sarret P, Spetea M, et al. Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure-Activity Relationship Studies. Journal of Medicinal Chemistry. PMID 32902268 DOI: 10.1021/Acs.Jmedchem.0C01376 |
0.674 |
|
| 2020 |
Besserer-Offroy É, Tétreault P, Brouillette RL, René A, Murza A, Fanelli R, Kirby K, Parent A, Dubuc I, Beaudet N, Côté J, Longpré JM, Martinez J, Cavelier F, Sarret P. Data set describing the biological activity of JMV2009, a novel silylated neurotensin(8-13) analog. Data in Brief. 31: 105884. PMID 32637491 DOI: 10.1016/J.Dib.2020.105884 |
0.818 |
|
| 2020 |
Previti S, Vivancos M, Rémond E, Beaulieu S, Longpré JM, Ballet S, Sarret P, Cavelier F. Insightful Backbone Modifications Preventing Proteolytic Degradation of Neurotensin Analogs Improve NT-Induced Protective Hypothermia. Frontiers in Chemistry. 8: 406. PMID 32582624 DOI: 10.3389/Fchem.2020.00406 |
0.407 |
|
| 2020 |
Tétreault P, Besserer-Offroy É, Brouillette RL, René A, Murza A, Fanelli R, Kirby K, Parent AJ, Dubuc I, Beaudet N, Côté J, Longpré JM, Martinez J, Cavelier F, Sarret P. Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog. European Journal of Pharmacology. 173174. PMID 32534076 DOI: 10.1016/J.Ejphar.2020.173174 |
0.827 |
|
| 2020 |
Girard M, Dagenais Bellefeuille S, Eiselt É, Brouillette R, Placet M, Arguin G, Longpré JM, Sarret P, Gendron FP. The P2Y receptor signals through Gα /Ca /PKCα and Gα /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration. Journal of Cellular Physiology. PMID 32420639 DOI: 10.1002/Jcp.29779 |
0.33 |
|
| 2020 |
Eiselt E, Otis V, Belleville K, Yang G, Larocque A, Regina A, Demeule M, Sarret P, Gendron L. Use of a non-invasive brain penetrating peptide-drug conjugate strategy to improve the delivery of opioid pain relief medications to the brain. The Journal of Pharmacology and Experimental Therapeutics. PMID 32327529 DOI: 10.1124/Jpet.119.263566 |
0.613 |
|
| 2020 |
Brouillette RL, Besserer-Offroy É, Mona CE, Chartier M, Lavenus S, Sousbie M, Belleville K, Longpré JM, Marsault É, Grandbois M, Sarret P. Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain. Pharmacological Research. 104750. PMID 32151680 DOI: 10.1016/J.Phrs.2020.104750 |
0.768 |
|
| 2020 |
Barrière DA, Midavaine É, Doré-Savard L, Kirby K, Tremblay L, Beaudoin JF, Beaudet N, Longpré JM, Lecomte R, Lepage M, Sarret P. Publisher Correction: Dichotomic effects of clinically used drugs on tumor growth, bone remodeling and pain management. Scientific Reports. 10: 2979. PMID 32060338 DOI: 10.1038/S41598-020-59781-Y |
0.769 |
|
| 2019 |
André Barrière D, Midavaine É, Doré-Savard L, Kirby K, Tremblay L, Beaudoin JF, Beaudet N, Longpré JM, Lecomte R, Lepage M, Sarret P. Dichotomic effects of clinically used drugs on tumor growth, bone remodeling and pain management. Scientific Reports. 9: 20155. PMID 31882872 DOI: 10.1038/S41598-019-56622-5 |
0.794 |
|
| 2019 |
Gusach A, Luginina A, Marin E, Brouillette RL, Besserer-Offroy É, Longpré JM, Ishchenko A, Popov P, Patel N, Fujimoto T, Maruyama T, Stauch B, Ergasheva M, Romanovskaia D, Stepko A, ... ... Sarret P, et al. Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors. Nature Communications. 10: 5573. PMID 31811124 DOI: 10.1038/s41467-019-13348-2 |
0.705 |
|
| 2019 |
Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, et al. Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists. Science Advances. 5: eaax9115. PMID 31807708 DOI: 10.1126/Sciadv.Aax9115 |
0.689 |
|
| 2019 |
Barrière DA, Boumezbeur F, Dalman R, Cadeddu R, Richard D, Pinguet J, Daulhac L, Sarret P, Whittingstall K, Keller M, Mériaux S, Eschalier A, Mallet C. Acetaminophen, a centrally-acting analgesic involving the periaqueductal grey. British Journal of Pharmacology. PMID 31734950 DOI: 10.1111/Bph.14934 |
0.77 |
|
| 2019 |
Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, ... ... Sarret P, et al. Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs. Science Advances. 5: eaax2518. PMID 31633023 DOI: 10.1126/Sciadv.Aax2518 |
0.714 |
|
| 2019 |
Eiselt E, Gonzalez S, Martin C, Chartier M, Betti C, Longpré JM, Cavelier F, Tourwè D, Gendron L, Ballet S, Sarret P. Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia. Acs Chemical Neuroscience. PMID 31589400 DOI: 10.1021/Acschemneuro.9B00390 |
0.672 |
|
| 2019 |
Boulkeroua C, Ayari H, Khalfaoui T, Lafrance M, Besserer-Offroy É, Ekindi N, Sabbagh R, Dumaine R, Lesur O, Sarret P, Chraibi A. Apelin-13 Regulates Vasopressin-Induced Aquaporin-2 Expression and Trafficking in Kidney Collecting Duct Cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 53: 687-700. PMID 31577078 DOI: 10.33594/000000165 |
0.704 |
|
| 2019 |
Eiselt E, Côté J, Longpré JM, Blais V, Sarret P, Gendron L. The combination of opioid and neurotensin receptor agonists improves their analgesic/adverse effect ratio. European Journal of Pharmacology. PMID 30707956 DOI: 10.1016/J.Ejphar.2019.01.048 |
0.627 |
|
| 2019 |
Besserer-Offroy E, Sarret P. Sending out Biased Signals: an Appropriate Proposition for Pain? Douleur Et AnalgéSie. 32: 108-110. DOI: 10.3166/Dea-2019-0065 |
0.758 |
|
| 2018 |
Normandeau CP, Torruella Suárez ML, Sarret P, McElligott ZA, Dumont EC. Neurotensin and dynorphin Bi-Directionally modulate CeA inhibition of oval BNST neurons in male mice. Neuropharmacology. 143: 113-121. PMID 30248304 DOI: 10.1016/J.Neuropharm.2018.09.031 |
0.313 |
|
| 2018 |
Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S. Corrigendum to "Chemical space screening around Phe in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings" [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320-2323]. Bioorganic & Medicinal Chemistry Letters. PMID 30195888 DOI: 10.1016/J.Bmcl.2018.08.023 |
0.602 |
|
| 2018 |
Sousbie M, Vivancos M, Brouillette RL, Besserer-Offroy É, Longpré JM, Leduc R, Sarret P, Marsault É. Structural Optimization and Characterization of Potent Analgesic Macrocyclic Analogues of Neurotensin (8-13). Journal of Medicinal Chemistry. PMID 30035538 DOI: 10.1021/Acs.Jmedchem.8B00175 |
0.733 |
|
| 2018 |
Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S. Chemical space screening around Phe in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings. Bioorganic & Medicinal Chemistry Letters. PMID 29853330 DOI: 10.1016/J.Bmcl.2018.05.015 |
0.667 |
|
| 2018 |
Sousbie M, Besserer-Offroy É, Brouillette RL, Longpré JM, Leduc R, Sarret P, Marsault É. In Search of the Optimal Macrocyclization Site for Neurotensin. Acs Medicinal Chemistry Letters. 9: 227-232. PMID 29541365 DOI: 10.1021/Acsmedchemlett.7B00500 |
0.697 |
|
| 2018 |
Besserer-Offroy É, Bérubé P, Côté J, Murza A, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Marsault É, Sarret P. The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment. Pharmacological Research. PMID 29530600 DOI: 10.1016/J.Phrs.2018.02.032 |
0.724 |
|
| 2018 |
Tran K, Murza A, Sainsily X, Coquerel D, Côté J, Belleville K, Haroune L, Longpré JM, Dumaine R, Salvail D, Lesur O, Auger-Messier M, Sarret P, Marsault É. A systematic exploration of macrocyclization in apelin-13 - impact on binding, signaling, stability and cardiovascular effects. Journal of Medicinal Chemistry. PMID 29461833 DOI: 10.1021/Acs.Jmedchem.7B01353 |
0.364 |
|
| 2018 |
Barrière DA, Noll C, Roussy G, Lizotte F, Kessai A, Kirby K, Belleville K, Beaudet N, Longpré JM, Carpentier AC, Geraldes P, Sarret P. Combination of high-fat/high-fructose diet and low-dose streptozotocin to model long-term type-2 diabetes complications. Scientific Reports. 8: 424. PMID 29323186 DOI: 10.1038/S41598-017-18896-5 |
0.73 |
|
| 2017 |
Van der Poorten O, Van Den Hauwe R, Eiselt E, Betti C, Guillemyn K, Chung NN, Hallé F, Bihel F, Schiller PW, Tourwé D, Sarret P, Gendron L, Ballet S. χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds. Acs Medicinal Chemistry Letters. 8: 1177-1182. PMID 29152051 DOI: 10.1021/Acsmedchemlett.7B00347 |
0.657 |
|
| 2017 |
Ferland CE, Parent AJ, Saran N, Ingelmo PM, Lacasse A, Marchand S, Sarret P, Ouellet JA. Preoperative Norepinephrine Levels in Cerebrospinal Fluid and Plasma Correlate With Pain Intensity After Pediatric Spine Surgery. Spine Deformity. 5: 325-333. PMID 28882350 DOI: 10.1016/J.Jspd.2017.03.012 |
0.37 |
|
| 2017 |
Coquerel D, Chagnon F, Sainsily X, Dumont L, Murza A, Côté J, Dumaine R, Sarret P, Marsault É, Salvail D, Auger-Messier M, Lesur O. ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock. Critical Care Medicine. PMID 28777197 DOI: 10.1097/Ccm.0000000000002639 |
0.333 |
|
| 2017 |
Fanelli R, Floquet N, Besserer-Offroy É, Delort B, Vivancos M, Longpré JM, Renault P, Martinez J, Sarret P, Cavelier F. Use of Molecular Modeling to Design Selective-NTS2 Neurotensin Analogues. Journal of Medicinal Chemistry. PMID 28368584 DOI: 10.1021/Acs.Jmedchem.6B01848 |
0.728 |
|
| 2017 |
Besserer-Offroy É, Brouillette RL, Lavenus S, Froehlich U, Brumwell A, Murza A, Longpré JM, Marsault É, Grandbois M, Sarret P, Leduc R. The signaling signature of the neurotensin type 1 receptor with endogenous ligands. European Journal of Pharmacology. PMID 28341345 DOI: 10.1016/J.Ejphar.2017.03.046 |
0.715 |
|
| 2017 |
Choinière M, Ware MA, Pagé MG, Lacasse A, Lanctôt H, Beaudet N, Boulanger A, Bourgault P, Cloutier C, Coupal L, De Koninck Y, Dion D, Dolbec P, Germain L, Martin V, ... Sarret P, et al. Development and Implementation of a Registry of Patients Attending Multidisciplinary Pain Treatment Clinics: The Quebec Pain Registry. Pain Research & Management. 2017: 8123812. PMID 28280406 DOI: 10.1155/2017/8123812 |
0.334 |
|
| 2016 |
Murza A, Sainsily X, Côté J, Bruneau-Cossette L, Besserer-Offroy É, Longpré JM, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault É. Structure-activity relationship of novel macrocyclic biased apelin receptor agonists. Organic & Biomolecular Chemistry. PMID 27924341 DOI: 10.1039/C6Ob02247B |
0.752 |
|
| 2016 |
Thomas JB, Vivancos M, Giddings AM, Wiethe RW, Warner KR, Murza A, Besserer-Offroy É, Longpre JM, Runyon SP, Decker AM, Gilmour BP, Sarret P. Identification of 2-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic acid (NTRC-844) as a selec-tive antagonist for the Rat Neurotensin recep-tor type 2. Acs Chemical Neuroscience. PMID 27359371 DOI: 10.1021/Acschemneuro.6B00097 |
0.767 |
|
| 2016 |
Otis C, Gervais J, Guillot M, Gervais JA, Gauvin D, Péthel C, Authier S, Dansereau MA, Sarret P, Martel-Pelletier J, Pelletier JP, Beaudry F, Troncy E. Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model. Arthritis Research & Therapy. 18: 150. PMID 27338815 DOI: 10.1186/S13075-016-1047-5 |
0.373 |
|
| 2016 |
Bégin-Lavallée V, Midavaine É, Dansereau MA, Tétreault P, Longpré JM, Jacobi AM, Rose SD, Behlke MA, Beaudet N, Sarret P. Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain development. Molecular Pain. 12. PMID 27306408 DOI: 10.1177/1744806916653969 |
0.708 |
|
| 2016 |
Murza A, Sainsily X, Coquerel D, Côté J, Marx P, Besserer-Offroy É, Longpre JM, Lainé J, Reversade B, Salvail D, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, et al. Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions. Journal of Medicinal Chemistry. PMID 26986036 DOI: 10.1021/Acs.Jmedchem.5B01549 |
0.738 |
|
| 2016 |
Ferland C, Parent A, Saran N, Ingelmo P, Marchand S, Sarret P, Ouellet J. Preoperative Norepinephrine Levels in Cerebrospinal Fluid and Plasma of Pediatric Patients Predict Postoperative Pain Intensity after Spinal Fusion Surgery Global Spine Journal. 6: s-0036-1582703-s-003. DOI: 10.1055/S-0036-1582703 |
0.347 |
|
| 2016 |
Hapəu D, Rémond E, Fanelli R, Vivancos M, René A, Côté J, Besserer-Offroy É, Longpré JM, Martinez J, Zaharia V, Sarret P, Cavelier F. Stereoselective Synthesis of β-(5-Arylthiazolyl) α-Amino Acids and Use in Neurotensin Analogues European Journal of Organic Chemistry. 2016: 1017-1024. DOI: 10.1002/Ejoc.201501495 |
0.706 |
|
| 2015 |
Parent AJ, Tétreault P, Roux M, Belleville K, Longpré JM, Beaudet N, Goffaux P, Sarret P. Descending nociceptive inhibition is modulated in a time-dependent manner in a double-hit model of chronic / tonic pain. Neuroscience. PMID 26691963 DOI: 10.1016/J.Neuroscience.2015.11.065 |
0.698 |
|
| 2015 |
Fanelli R, Besserer-Offroy É, René A, Côté J, Tétreault P, Collerette-Tremblay J, Longpré JM, Leduc R, Martinez J, Sarret P, Cavelier F. Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues. Journal of Medicinal Chemistry. 58: 7785-95. PMID 26348111 DOI: 10.1021/Acs.Jmedchem.5B00841 |
0.81 |
|
| 2015 |
Thomas JB, Giddings AM, Olepu S, Wiethe RW, Warner KR, Sarret P, Longpre JM, Runyon SP, Gilmour BP. The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2. Bioorganic & Medicinal Chemistry Letters. 25: 2060-4. PMID 25881832 DOI: 10.1016/J.Bmcl.2015.03.083 |
0.405 |
|
| 2015 |
Murza A, Besserer-Offroy É, Côté J, Bérubé P, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Sarret P, Marsault É. C-Terminal modifications of apelin-13 significantly change ligand binding, receptor signaling, and hypotensive action. Journal of Medicinal Chemistry. 58: 2431-40. PMID 25668242 DOI: 10.1021/Jm501916K |
0.75 |
|
| 2015 |
Parent AJ, Beaudet N, Daigle K, Sabbagh R, Sansoucy Y, Marchand S, Sarret P, Goffaux P. Relationship between blood- and cerebrospinal fluid-bound neurotransmitter concentrations and conditioned pain modulation in pain-free and chronic pain subjects. The Journal of Pain : Official Journal of the American Pain Society. 16: 436-44. PMID 25659204 DOI: 10.1016/J.Jpain.2015.01.007 |
0.39 |
|
| 2015 |
Thomas JB, Giddings AM, Olepu S, Wiethe RW, Harris DL, Narayanan S, Warner KR, Sarret P, Longpre JM, Runyon SP, Gilmour BP. Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2. Bioorganic & Medicinal Chemistry Letters. 25: 292-6. PMID 25499438 DOI: 10.1016/J.Bmcl.2014.11.047 |
0.387 |
|
| 2014 |
Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP. Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2. Journal of Medicinal Chemistry. 57: 7472-7. PMID 25157640 DOI: 10.1021/Jm500857R |
0.668 |
|
| 2014 |
Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP. Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound. Journal of Medicinal Chemistry. 57: 5318-32. PMID 24856674 DOI: 10.1021/Jm5003843 |
0.657 |
|
| 2014 |
Murza A, Belleville K, Longpré JM, Sarret P, Marsault E. Stability and degradation patterns of chemically modified analogs of apelin-13 in plasma and cerebrospinal fluid. Biopolymers. 101: 297-303. PMID 24728860 DOI: 10.1002/Bip.22498 |
0.313 |
|
| 2014 |
Demeule M, Beaudet N, Régina A, Besserer-Offroy É, Murza A, Tétreault P, Belleville K, Ché C, Larocque A, Thiot C, Béliveau R, Longpré JM, Marsault É, Leduc R, Lachowicz JE, ... ... Sarret P, et al. Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties. The Journal of Clinical Investigation. 124: 1199-213. PMID 24531547 DOI: 10.1172/Jci70647 |
0.817 |
|
| 2014 |
Beaudet N, Courteau J, Sarret P, Vanasse A. Improving the selection of true incident cases of low back pain by screening retrospective administrative data. European Journal of Pain (London, England). 18: 923-31. PMID 24343901 DOI: 10.1002/J.1532-2149.2013.00437.X |
0.337 |
|
| 2013 |
Tétreault P, Beaudet N, Perron A, Belleville K, René A, Cavelier F, Martinez J, Stroh T, Jacobi AM, Rose SD, Behlke MA, Sarret P. Spinal NTS2 receptor activation reverses signs of neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3741-52. PMID 23756650 DOI: 10.1096/Fj.12-225540 |
0.731 |
|
| 2013 |
Beaudet N, Courteau J, Sarret P, Vanasse A. Prevalence of claims-based recurrent low back pain in a Canadian population: a secondary analysis of an administrative database. Bmc Musculoskeletal Disorders. 14: 151. PMID 23628144 DOI: 10.1186/1471-2474-14-151 |
0.327 |
|
| 2013 |
Doré-Savard L, Barrière DA, Midavaine É, Bélanger D, Beaudet N, Tremblay L, Beaudoin JF, Turcotte EE, Lecomte R, Lepage M, Sarret P. Mammary cancer bone metastasis follow-up using multimodal small-animal MR and PET imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 944-52. PMID 23596003 DOI: 10.2967/Jnumed.112.114215 |
0.747 |
|
| 2013 |
Doré-Savard L, Beaudet N, Tremblay L, Xiao Y, Lepage M, Sarret P. A micro-imaging study linking bone cancer pain with tumor growth and bone resorption in a rat model. Clinical & Experimental Metastasis. 30: 225-36. PMID 22956259 DOI: 10.1007/S10585-012-9530-0 |
0.786 |
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| 2013 |
Beaudet N, Courteau J, Michaud F, Sarret P, Vanasse A. Descriptive analysis of claims-based recurrent low back pain F1000research. 4. DOI: 10.7490/F1000Research.1094813.1 |
0.36 |
|
| 2012 |
Guillemette A, Dansereau MA, Beaudet N, Richelson E, Sarret P. Intrathecal administration of NTS1 agonists reverses nociceptive behaviors in a rat model of neuropathic pain. European Journal of Pain (London, England). 16: 473-84. PMID 22396077 DOI: 10.1016/J.Ejpain.2011.07.008 |
0.453 |
|
| 2012 |
Parent AJ, Beaudet N, Beaudry H, Bergeron J, Bérubé P, Drolet G, Sarret P, Gendron L. Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain. Behavioural Brain Research. 229: 160-7. PMID 22245257 DOI: 10.1016/J.Bbr.2012.01.001 |
0.645 |
|
| 2012 |
Murza A, Parent A, Besserer-Offroy E, Tremblay H, Karadereye F, Beaudet N, Leduc R, Sarret P, Marsault É. Elucidation of the structure-activity relationships of apelin: influence of unnatural amino acids on binding, signaling, and plasma stability. Chemmedchem. 7: 318-25. PMID 22170700 DOI: 10.1002/Cmdc.201100492 |
0.745 |
|
| 2011 |
Tétreault P, Dansereau MA, Doré-Savard L, Beaudet N, Sarret P. Weight bearing evaluation in inflammatory, neuropathic and cancer chronic pain in freely moving rats. Physiology & Behavior. 104: 495-502. PMID 21620878 DOI: 10.1016/J.Physbeh.2011.05.015 |
0.796 |
|
| 2011 |
Van Steenwinckel J, Reaux-Le Goazigo A, Pommier B, Mauborgne A, Dansereau MA, Kitabgi P, Sarret P, Pohl M, Mélik Parsadaniantz S. CCL2 released from neuronal synaptic vesicles in the spinal cord is a major mediator of local inflammation and pain after peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5865-75. PMID 21490228 DOI: 10.1523/Jneurosci.5986-10.2011 |
0.419 |
|
| 2011 |
Otis V, Sarret P, Gendron L. Spinal activation of delta opioid receptors alleviates cancer-related bone pain. Neuroscience. 183: 221-9. PMID 21458544 DOI: 10.1016/J.Neuroscience.2011.03.052 |
0.698 |
|
| 2011 |
Sarret P, Doré-Savard L, Tétreault P, Bégin-Lavallée V, Dansereau MA, Beaudet N. Using RNA interference to downregulate G protein-coupled receptors Neuromethods. 60: 379-402. DOI: 10.1007/978-1-61779-179-6_19 |
0.769 |
|
| 2010 |
Doré-Savard L, Otis V, Belleville K, Lemire M, Archambault M, Tremblay L, Beaudoin JF, Beaudet N, Lecomte R, Lepage M, Gendron L, Sarret P. Behavioral, medical imaging and histopathological features of a new rat model of bone cancer pain. Plos One. 5: e13774. PMID 21048940 DOI: 10.1371/Journal.Pone.0013774 |
0.798 |
|
| 2010 |
Roussy G, Beaudry H, Lafrance M, Belleville K, Beaudet N, Wada K, Gendron L, Sarret P. Altered morphine-induced analgesia in neurotensin type 1 receptor null mice. Neuroscience. 170: 1286-94. PMID 20727387 DOI: 10.1016/J.Neuroscience.2010.08.016 |
0.681 |
|
| 2010 |
Sarret P, Doré-Savard L, Beaudet N. Direct application of siRNA for in vivo pain research. Methods in Molecular Biology (Clifton, N.J.). 623: 383-95. PMID 20217565 DOI: 10.1007/978-1-60761-588-0_25 |
0.802 |
|
| 2010 |
Lafrance M, Roussy G, Belleville K, Maeno H, Beaudet N, Wada K, Sarret P. Involvement of NTS2 receptors in stress-induced analgesia. Neuroscience. 166: 639-52. PMID 20035838 DOI: 10.1016/J.Neuroscience.2009.12.042 |
0.409 |
|
| 2010 |
Hwang JR, Baek MW, Sim J, Choi HS, Han JM, Kim YL, Hwang JI, Kwon HB, Beaudet N, Sarret P, Seong JY. Intermolecular cross-talk between NTR1 and NTR2 neurotensin receptor promotes intracellular sequestration and functional inhibition of NTR1 receptors. Biochemical and Biophysical Research Communications. 391: 1007-13. PMID 19968961 DOI: 10.1016/J.Bbrc.2009.12.007 |
0.394 |
|
| 2010 |
Roussy G, Lemire M, Belleville K, Beaudet N, Martinez J, Sarret P. Targeting the neurotensinergic system to soothe bone cancer pain F1000research. 1. DOI: 10.7490/F1000Research.495.1 |
0.363 |
|
| 2009 |
Roussy G, Dansereau MA, Baudisson S, Ezzoubaa F, Belleville K, Beaudet N, Martinez J, Richelson E, Sarret P. Evidence for a role of NTS2 receptors in the modulation of tonic pain sensitivity. Molecular Pain. 5: 38. PMID 19580660 DOI: 10.1186/1744-8069-5-38 |
0.464 |
|
| 2008 |
Gosselin RD, Dansereau MA, Pohl M, Kitabgi P, Beaudet N, Sarret P, Mélik Parsadaniantz S. Chemokine network in the nervous system: a new target for pain relief. Current Medicinal Chemistry. 15: 2866-75. PMID 18991641 DOI: 10.2174/092986708786242822 |
0.439 |
|
| 2008 |
Doré-Savard L, Roussy G, Dansereau MA, Collingwood MA, Lennox KA, Rose SD, Beaudet N, Behlke MA, Sarret P. Central delivery of Dicer-substrate siRNA: a direct application for pain research. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1331-9. PMID 18523447 DOI: 10.1038/Mt.2008.98 |
0.823 |
|
| 2008 |
Dansereau MA, Gosselin RD, Pohl M, Pommier B, Mechighel P, Mauborgne A, Rostene W, Kitabgi P, Beaudet N, Sarret P, Melik-Parsadaniantz S. Spinal CCL2 pronociceptive action is no longer effective in CCR2 receptor antagonist-treated rats. Journal of Neurochemistry. 106: 757-69. PMID 18419759 DOI: 10.1111/J.1471-4159.2008.05429.X |
0.445 |
|
| 2008 |
Roussy G, Dansereau MA, Doré-Savard L, Belleville K, Beaudet N, Richelson E, Sarret P. Spinal NTS1 receptors regulate nociceptive signaling in a rat formalin tonic pain model. Journal of Neurochemistry. 105: 1100-14. PMID 18182046 DOI: 10.1111/J.1471-4159.2007.05205.X |
0.818 |
|
| 2008 |
Larouche A, Berube P, Sarret P, Grignon S. Subacute H2O2, but not poly(IC), upregulates dopamine D2 receptors in retinoic acid differentiated SH-SY5Y neuroblastoma. Synapse (New York, N.Y.). 62: 70-3. PMID 17960767 DOI: 10.1002/Syn.20458 |
0.303 |
|
| 2007 |
Sharif N, Gendron L, Wowchuk J, Sarret P, Mazella J, Beaudet A, Stroh T. Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2. Endocrinology. 148: 2095-105. PMID 17272399 DOI: 10.1210/En.2006-1266 |
0.674 |
|
| 2007 |
Perron A, Sharif N, Sarret P, Stroh T, Beaudet A. NTS2 modulates the intracellular distribution and trafficking of NTS1 via heterodimerization. Biochemical and Biophysical Research Communications. 353: 582-90. PMID 17188644 DOI: 10.1016/J.Bbrc.2006.12.062 |
0.535 |
|
| 2006 |
Stroh T, Sarret P, Tannenbaum GS, Beaudet A. Immunohistochemical distribution and subcellular localization of the somatostatin receptor subtype 1 (sst1) in the rat hypothalamus. Neurochemical Research. 31: 247-57. PMID 16518576 DOI: 10.1007/S11064-005-9013-7 |
0.52 |
|
| 2005 |
Sarret P, Esdaile MJ, Perron A, Martinez J, Stroh T, Beaudet A. Potent spinal analgesia elicited through stimulation of NTS2 neurotensin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8188-96. PMID 16148226 DOI: 10.1523/Jneurosci.0810-05.2005 |
0.598 |
|
| 2005 |
Perron A, Sarret P, Gendron L, Stroh T, Beaudet A. Identification and functional characterization of a 5-transmembrane domain variant isoform of the NTS2 neurotensin receptor in rat central nervous system. The Journal of Biological Chemistry. 280: 10219-27. PMID 15637074 DOI: 10.1074/Jbc.M410557200 |
0.729 |
|
| 2004 |
Gendron L, Perron A, Payet MD, Gallo-Payet N, Sarret P, Beaudet A. Low-affinity neurotensin receptor (NTS2) signaling: internalization-dependent activation of extracellular signal-regulated kinases 1/2. Molecular Pharmacology. 66: 1421-30. PMID 15361549 DOI: 10.1124/Mol.104.002303 |
0.735 |
|
| 2004 |
Sarret P, Esdaile MJ, McPherson PS, Schonbrunn A, Kreienkamp HJ, Beaudet A. Role of amphiphysin II in somatostatin receptor trafficking in neuroendocrine cells. The Journal of Biological Chemistry. 279: 8029-37. PMID 14660576 DOI: 10.1074/Jbc.M310792200 |
0.556 |
|
| 2003 |
Sarret P, Perron A, Stroh T, Beaudet A. Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous system. The Journal of Comparative Neurology. 461: 520-38. PMID 12746866 DOI: 10.1002/Cne.10718 |
0.533 |
|
| 2003 |
Sarret P, Krzywkowski P, Segal L, Nielsen MS, Petersen CM, Mazella J, Stroh T, Beaudet A. Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system. The Journal of Comparative Neurology. 461: 483-505. PMID 12746864 DOI: 10.1002/Cne.10708 |
0.494 |
|
| 2002 |
Sarret P, Gendron L, Kilian P, Nguyen HM, Gallo-Payet N, Payet MD, Beaudet A. Pharmacology and functional properties of NTS2 neurotensin receptors in cerebellar granule cells. The Journal of Biological Chemistry. 277: 36233-43. PMID 12084713 DOI: 10.1074/Jbc.M202586200 |
0.726 |
|
| 2002 |
Sarret P, Beaudet A. Chapter VI Neurotensin receptors in the central nervous system Handbook of Chemical Neuroanatomy. 20: 323-400. DOI: 10.1016/S0924-8196(02)80008-2 |
0.482 |
|
| 2001 |
Navarro V, Martin S, Sarret P, Nielsen MS, Petersen CM, Vincent J, Mazella J. Pharmacological properties of the mouse neurotensin receptor 3. Maintenance of cell surface receptor during internalization of neurotensin. Febs Letters. 495: 100-5. PMID 11322955 DOI: 10.1016/S0014-5793(01)02367-5 |
0.386 |
|
| 2001 |
Dal Farra C, Sarret P, Navarro V, Botto JM, Mazella J, Vincent JP. Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines. International Journal of Cancer. Journal International Du Cancer. 92: 503-9. PMID 11304684 DOI: 10.1002/Ijc.1225 |
0.347 |
|
| 2000 |
Stroh T, Jackson AC, Sarret P, Dal Farra C, Vincent JP, Kreienkamp HR, Mazella J, Beaudet A. Intracellular Dynamics of sst5 Receptors in Transfected COS-7 Cells: Maintenance of Cell Surface Receptors during Ligand-Induced Endocytosis1. Endocrinology. 141: 354-365. PMID 28200938 DOI: 10.1210/endo.141.1.7259 |
0.467 |
|
| 2000 |
Boudin H, Sarret P, Mazella J, Schonbrunn A, Beaudet A. Somatostatin-induced regulation of SST(2A) receptor expression and cellsurface availability in central neurons: role of receptor internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5932-9. PMID 10934240 DOI: 10.1523/Jneurosci.20-16-05932.2000 |
0.529 |
|
| 2000 |
Stroh T, Jackson AC, Sarret P, Dal Farra C, Vincent JP, Kreienkamp HJ, Mazella J, Beaudet A. Intracellular dynamics of sst5 receptors in transfected COS-7 cells: maintenance of cell surface receptors during ligand-induced endocytosis. Endocrinology. 141: 354-65. PMID 10614658 DOI: 10.1210/Endo.141.1.7259 |
0.562 |
|
| 1999 |
Nouel D, Sarret P, Vincent JP, Mazella J, Beaudet A. Pharmacological, molecular and functional characterization of glial neurotensin receptors. Neuroscience. 94: 1189-97. PMID 10625058 DOI: 10.1016/S0306-4522(99)00354-1 |
0.544 |
|
| 1999 |
Sarret P, Nouel D, Dal Farra C, Vincent JP, Beaudet A, Mazella J. Receptor-mediated internalization is critical for the inhibition of the expression of growth hormone by somatostatin in the pituitary cell line AtT-20. The Journal of Biological Chemistry. 274: 19294-300. PMID 10383439 DOI: 10.1074/Jbc.274.27.19294 |
0.523 |
|
| 1999 |
Dubuc I, Sarret P, Labbé-Jullié C, Botto JM, Honoré E, Bourdel E, Martinez J, Costentin J, Vincent JP, Kitabgi P, Mazella J. Identification of the receptor subtype involved in the analgesic effect of neurotensin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 503-10. PMID 9870978 |
0.347 |
|
| 1999 |
Dubuc I, Sarret P, Labbé-Jullié C, Botto J, Honoré E, Bourdel E, Martinez J, Costentin J, Vincent J, Kitabgi P, Mazella J. Identification of the Receptor Subtype Involved in the Analgesic Effect of Neurotensin The Journal of Neuroscience. 19: 503-510. DOI: 10.1523/Jneurosci.19-01-00503.1999 |
0.45 |
|
| 1998 |
Sarret P, Botto JM, Vincent JP, Mazella J, Beaudet A. Preferential expression of sst2A over sst2B somatostatin receptor splice variant in rat brain and pituitary. Neuroendocrinology. 68: 37-43. PMID 9695937 DOI: 10.1159/000054348 |
0.51 |
|
| 1998 |
Sarret P, Beaudet A, Vincent JP, Mazella J. Regional and cellular distribution of low affinity neurotensin receptor mRNA in adult and developing mouse brain. The Journal of Comparative Neurology. 394: 344-56. PMID 9579398 DOI: 10.1002/(Sici)1096-9861(19980511)394:3<344::Aid-Cne6>3.0.Co;2-1 |
0.522 |
|
| 1998 |
Botto JM, Chabry J, Sarret P, Vincent JP, Mazella J. Stable expression of the mouse levocabastine-sensitive neurotensin receptor in HEK 293 cell line: binding properties, photoaffinity labeling, and internalization mechanism. Biochemical and Biophysical Research Communications. 243: 585-90. PMID 9480852 DOI: 10.1006/Bbrc.1997.8071 |
0.399 |
|
| 1997 |
Botto JM, Sarret P, Vincent JP, Mazella J. Identification and expression of a variant isoform of the levocabastine-sensitive neurotensin receptor in the mouse central nervous system. Febs Letters. 400: 211-4. PMID 9001400 DOI: 10.1016/S0014-5793(96)01391-9 |
0.383 |
|
| 1996 |
Mazella J, Botto JM, Guillemare E, Coppola T, Sarret P, Vincent JP. Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5613-20. PMID 8795617 DOI: 10.1523/Jneurosci.16-18-05613.1996 |
0.396 |
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