W Scott Young, M.D., Ph.D.

Affiliations: 
Section on Neural Gene Expression NIMH, NIH, Bethesda, MD, Bethesda, MD, United States 
Area:
oxytocin, vasopressin, behavior
Website:
http://www.nimh.nih.gov/labs-at-nimh/research-areas/clinics-and-labs/lcmr/snge/index.shtml
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"W Scott Young"
Bio:

Dr. Young received his B.A., M.D., and Ph.D from The Johns Hopkins University. The latter degree, obtained under the guidance of Michael Kuhar, described the development of in vitro receptor autoradiography and the first applications of the technique to the localization of neurotranmsitter receptors in human and other animal brains. Dr. Young then completed an internship in internal medicine at the University of Maryland and a residency in neurology at the University of Virginia. He joined the NIMH in 1984 where he has studied the paraventricular and supraoptic nuclei in the hypothalamus. Dr. Young's laboratory is currently using and creating knock-out and transgenic mice to study the roles of vasopressin and oxytocin in the brain.

Mean distance: 13.85 (cluster 6)
 
SNBCP

Parents

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Saul Roseman research assistant 1971-1972 Johns Hopkins (Chemistry Tree)
Julius Axelrod research assistant 1975 NIMH
 (Summer student)
Michael J. Kuhar grad student 1977-1980 Johns Hopkins
Michael Brownstein post-doc 1984-1990 NIMH, NIH, Bethesda, MD
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Publications

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Smith AS, Williams Avram SK, Cymerblit-Sabba A, et al. (2016) Targeted activation of the hippocampal CA2 area strongly enhances social memory. Molecular Psychiatry
Pagani JH, Williams Avram SK, Cui Z, et al. (2015) Raphe serotonin neuron-specific oxytocin receptor knockout reduces aggression without affecting anxiety-like behavior in male mice only. Genes, Brain, and Behavior. 14: 167-76
Pagani JH, Zhao M, Cui Z, et al. (2015) Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2. Molecular Psychiatry. 20: 490-9
Young WS. (2013) Shedding heat on oxytocin. Endocrinology. 154: 3961-2
Choi JW, Kang SM, Lee Y, et al. (2013) MicroRNA profiling in the mouse hypothalamus reveals oxytocin-regulating microRNA. Journal of Neurochemistry. 126: 331-7
Hammoudeh M, Alarfaj A, Chen DY, et al. (2013) Safety of tumor necrosis factor inhibitors use for rheumatoid arthritis and ankylosing spondylitis in Africa, the Middle East, and Asia: focus on severe infections and tuberculosis. Clinical Rheumatology. 32: 293-300
Cui Z, Gerfen CR, Young WS. (2013) Hypothalamic and other connections with dorsal CA2 area of the mouse hippocampus. The Journal of Comparative Neurology. 521: 1844-66
Sanek NA, Young WS. (2012) Investigating the in vivo expression patterns of miR-7 microRNA family members in the adult mouse brain. Microrna (ShāRiqah, United Arab Emirates). 1: 11-8
Colaianni G, Sun L, Di Benedetto A, et al. (2012) Bone marrow oxytocin mediates the anabolic action of estrogen on the skeleton. The Journal of Biological Chemistry. 287: 29159-67
Pobbe RL, Pearson BL, Defensor EB, et al. (2012) Oxytocin receptor knockout mice display deficits in the expression of autism-related behaviors. Hormones and Behavior. 61: 436-44
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