Julius Axelrod, PhD

Affiliations: 
National Institute of Mental Health, Bethesda, MD, United States 
Area:
Neurotransmitters
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1970/axelrod-bio.html
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"Julius Axelrod"
Bio:

(1912 - 2004)
http://www.nasonline.org/member-directory/deceased-members/58106.html
http://www.nap.edu/openbook.php?record_id=11522&page=74
http://profiles.nlm.nih.gov/ps/retrieve/Collection/CID/HH
http://en.wikipedia.org/wiki/Julius_Axelrod
The Nobel Prize in Physiology or Medicine 1970 was awarded jointly to Sir Bernard Katz, Ulf von Euler and Julius Axelrod "for their discoveries concerning the humoral transmittors in the nerve terminals and the mechanism for their storage, release and inactivation".

Mean distance: 12.17 (cluster 6)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Bernard Beryl Brodie research assistant 1946-1949 Goldwater Memorial Hospital
H. George Mandel grad student 1954-1955 George Washington University (Chemistry Tree)
 (The Fate of Phenylisopropylamines)

Children

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W Scott Young research assistant 1975 NIMH
Warren J. Strittmatter grad student
Ira B. Black post-doc NIMH
Christian C. Felder post-doc National Institutes of Mental Health (Chemistry Tree)
Jacques Glowinski post-doc CBDB, GCAP, NIMH, DIRP, NIH
Ronald W. Holz post-doc University of Michigan
Leslie Iversen post-doc Oxford
Solomon H. Snyder post-doc NIMH
John Tallman post-doc NIMH
Richard Weinshilboum post-doc NIMH (Cell Biology Tree)
Richard J. Wurtman post-doc 1962 NIMH
Arthur Michaelson post-doc 1960-1965 NIH
Jacques de Champlain post-doc 1966 NIMH (E-Tree)
Saul Murray Schanberg post-doc 1965-1967 NIMH
Hans Thoenen post-doc 1968-1969 NIMH
Richard J. Wyatt post-doc 1968-1969 NIMH
Perry Molinoff post-doc 1967-1970 NIMH
Louis Lemberger post-doc 1968-1972 NIMH
Joseph T. Coyle post-doc 1970-1973 National Institutes of Mental Health
Fulton T. Crews post-doc 1978-1980 NIMH/NIH
Juan Saavedra post-doc 1971-1984
Bruce  R. Conklin post-doc 1986-1988 NIMH
Michael Brownstein research scientist NIH
Morris A. Lipton research scientist NIMH, NIH
Arthur J. Prange, Jr. research scientist NIMH/NIH
Irwin J. Kopin research scientist 1963-1968 NIMH
BETA: Related publications

Publications

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AXELROD J, INSCOE JK, SENOH S, et al. (2000) O-methylation, the principal pathway for the metabolism of epinephrine and norepinephrine in the rat. Biochimica Et Biophysica Acta. 27: 210-1
HERTTING G, AXELROD J, PATRICK RW. (1998) Actions of bretylium and guanethidine on the uptake and release of [3H]-noradrenaline. British Journal of Pharmacology and Chemotherapy. 18: 161-6
DALY J, AXELROD J, WITKOP B. (1998) Methylation and demethylation in relation to the in vitro metabolism of mescaline. Annals of the New York Academy of Sciences. 96: 37-43
AXELROD J, HERTTING G, POTTER L. (1998) Effect of drugs on the uptake and release of 3H-norepinephrine in the rat heart. Nature. 194: 297
Axelrod J, Felder CC. (1998) Cannabinoid receptors and their endogenous agonist, anandamide. Neurochemical Research. 23: 575-81
DALY J, INSCOE JK, AXELROD J. (1996) THE FORMATION OF O-METHYLATED CATECHOLS BY MICROSOMAL HYDROXYLATION OF PHENOLS AND SUBSEQUENT ENZYMATIC CATECHOL O-METHYLATION. SUBSTRATE SPECIFICITY. Journal of Medicinal Chemistry. 8: 153-7
Felder CC, Nielsen A, Briley EM, et al. (1996) Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat. Febs Letters. 393: 231-5
Devane WA, Axelrod J. (1994) Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. Proceedings of the National Academy of Sciences of the United States of America. 91: 6698-701
Briley EM, Lolait SJ, Axelrod J, et al. (1994) The cloned vasopressin V1a receptor stimulates phospholipase A2, phospholipase C, and phospholipase D through activation of receptor-operated calcium channels. Neuropeptides. 27: 63-74
Felder CC, Briley EM, Axelrod J, et al. (1993) Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 90: 7656-60
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