Filip Van Petegem, Ph.D.

Affiliations: 
Biochemistry and Molecular Biology University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
voltage-gated sodium and calcium channels, Ryanodine Receptors
Website:
http://crg.ubc.ca/VanPetegem/
Google:
"Filip Van Petegem"
Mean distance: 15.68 (cluster 6)
 
SNBCP

Parents

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Dan Minor post-doc 2002-2007 UCSF
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Publications

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Chen YS, Garcia-Castañeda M, Charalambous M, et al. (2024) Cryo-EM investigation of ryanodine receptor type 3. Nature Communications. 15: 8630
Joseph TT, Bu W, Haji-Ghassemi O, et al. (2024) Propofol binds and inhibits skeletal muscle ryanodine receptor 1. British Journal of Anaesthesia
Collaço RC, Van Petegem F, Bosmans F. (2024) ω-Grammotoxin-SIA inhibits voltage-gated Na+ channel currents. The Journal of General Physiology. 156
Joseph TT, Bu W, Haji-Ghassemi O, et al. (2024) Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1). Biorxiv : the Preprint Server For Biology
Šeflová J, Schwarz JA, Smith AN, et al. (2023) RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET. Acs Chemical Biology
Haji-Ghassemi O, Chen YS, Woll K, et al. (2023) Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation. Science Advances. 9: eadf4936
Cholak S, Saville JW, Zhu X, et al. (2023) Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure (London, England : 1993)
Chen YS, Van Petegem F. (2022) Structural and functional conservation of the activating Ca binding site in inositol 1,4.5-trisphosphate and ryanodine receptors. Cell Calcium. 108: 102671
Rayani K, Hantz ER, Haji-Ghassemi O, et al. (2022) The effect of Mg on Ca binding to cardiac troponin C in hypertrophic cardiomyopathy associated TNNC1 variants. The Febs Journal
Willegems K, Eldstrom J, Kyriakis E, et al. (2022) Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277. Nature Communications. 13: 3760
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