Ashley Lepack
Affiliations: | 2015- | Pharmacology & Systems Therapeutics | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
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Publications
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| Banasr M, Codeluppi S, Xu M, et al. (2023) Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior. Research Square |
| Al-Kachak A, Fulton SL, Farrelly LA, et al. (2023) Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior. Biorxiv : the Preprint Server For Biology |
| Fulton SL, Bendl J, Gameiro-Ros I, et al. (2023) ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex. Biorxiv : the Preprint Server For Biology |
| Finkin-Groner E, Al-Kachak A, Agustinus A, et al. (2023) Flexible and site-specific manipulation of histones in live animals. Biorxiv : the Preprint Server For Biology |
| Stewart AF, Lepack AL, Fulton SL, et al. (2023) Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence. Molecular and Cellular Neurosciences. 125: 103824 |
| Fulton SL, Wenderski W, Lepack AE, et al. (2022) Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature Communications. 13: 6384 |
| Fulton SL, Mitra S, Lepack AE, et al. (2022) Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology |
| Lepack AE, Werner CT, Stewart AF, et al. (2020) Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.). 368: 197-201 |
| Werner CT, Mitra S, Martin JA, et al. (2019) Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving. Science Advances. 5: eaay0351 |
| Lorsch ZS, Hamilton PJ, Ramakrishnan A, et al. (2019) Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. Nature Neuroscience |