Yusuf A. Hannun, M.D.
Affiliations: | 1983-1998 | Medicine | Duke University, Durham, NC |
| 1998-2012 | Biochemistry | Medical University of South Carolina, Charleston, SC, United States | |
| 2012- | Cancer Center | Stony Brook University, Stony Brook, NY, United States |
Area:
cancer biology, Lipid biology, lipid singingGoogle:
"Yusuf Hannun"Children
Sign in to add trainee| Heather L. Hayter | grad student | 2000 | Duke |
| Gary M. Jenkins | grad student | 2000 | Duke |
| Kelley Argraves | post-doc | 1998-2001 | MUSC (Chemistry Tree) |
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Publications
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| Truman JP, Ruiz CF, Montal E, et al. (2021) 1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase. Journal of Lipid Research. 63: 100154 |
| Truman JP, Ruiz CF, Trayssac M, et al. (2021) Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21284 |
| Zhang X, Sakamoto W, Canals D, et al. (2021) Ceramide synthase 2-C -ceramide axis limits the metastatic potential of ovarian cancer cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21287 |
| Thayyullathil F, Cheratta AR, Alakkal A, et al. (2021) Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis. Cell Death & Disease. 12: 26 |
| Zhao D, Hajiaghamohseni LM, Liu X, et al. (2020) Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis. Cytokine. 135: 155219 |
| Shanbhogue P, Hoffmann RM, Airola MV, et al. (2019) The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme. The Journal of Biological Chemistry |
| Sakamoto W, Coant N, Canals D, et al. (2018) Functions of neutral ceramidase in the Golgi apparatus. Journal of Lipid Research |
| Carroll BL, Bonica J, Shamseddine AA, et al. (2018) A role for caspase-2 in sphingosine kinase 1 proteolysis in response to doxorubicin in breast cancer cells - implications for the CHK1-suppressed pathway. Febs Open Bio. 8: 27-40 |
| Liu M, Clarke CJ, Salama MF, et al. (2017) Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation. Plos One. 12: e0184818 |
| García-Barros M, Coant N, Kawamori T, et al. (2016) Role of neutral ceramidase in colon cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |