Sara P. Faccidomo

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Alcohol abuse and alcoholism
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"Sara Faccidomo"
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Parents

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Klaus A. Miczek grad student 2006 Tufts
 (Alcohol and aggression: A role for the 5-HT(1B) receptor in the prefrontal cortex and the dorsal raphe nucleus.)
Clyde W. Hodge post-doc 2007- UNC Chapel Hill
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Publications

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Faccidomo S, Eastman VR, Santanam TS, et al. (2024) Sex Differences in Home-Cage Ethanol Drinking and Operant Self-Administration in C57BL/6J Mice but Equivalent Regulation by Glutamate AMPAR Activity. Biorxiv : the Preprint Server For Biology
Faccidomo S, Saunders BL, May AM, et al. (2024) Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug. Biorxiv : the Preprint Server For Biology
Hoffman JL, Faccidomo SP, Taylor SM, et al. (2023) Negative modulation of AMPA receptors bound to transmembrane AMPA receptor regulatory protein γ-8 blunts the positive reinforcing properties of alcohol and sucrose in a brain region-dependent manner in male mice. Psychopharmacology
Echeveste Sanchez M, Quadir SG, Whindleton CM, et al. (2022) The effects of electronic nicotine vapor on voluntary alcohol consumption in female and male C57BL/6 J mice. Drug and Alcohol Dependence. 241: 109676
Hoffman JL, Faccidomo S, Saunders BL, et al. (2021) Inhibition of AMPA receptors containing TARP γ-8 with JNJ-55511118 shows preclinical efficacy for pharmacotherapeutic treatment of chronic repetitive alcohol self-administration. Alcoholism, Clinical and Experimental Research
Faccidomo S, Cogan ES, Hon OJ, et al. (2021) Calcium-permeable AMPA receptor activity and GluA1 trafficking in the basolateral amygdala regulate operant alcohol self-administration. Addiction Biology. e13049
Luisa Torruella-Suárez M, Vandenberg JR, Cogan ES, et al. (2019) Manipulations of central amygdala neurotensin neurons alter the consumption of ethanol and sweet fluids in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Hoffman JL, Faccidomo S, Kim M, et al. (2019) Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. International Review of Neurobiology. 148: 169-230
Faccidomo S, Holstein SE, Santanam TS, et al. (2019) Pharmacological inhibition of glycogen synthase kinase 3 increases operant alcohol self-administration in a manner associated with altered pGSK-3β, protein interacting with C kinase and GluA2 protein expression in the reward pathway of male C57BL/6J mice. Behavioural Pharmacology
Stevenson RA, Hoffman JL, Maldonado-Devincci AM, et al. (2019) MGluR5 activity is required for the induction of ethanol behavioral sensitization and associated changes in ERK MAP kinase phosphorylation in the nucleus accumbens shell and lateral habenula. Behavioural Brain Research
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