David Malcolm MacLean, PhD
Affiliations: | 2017- | Pharmacology and Physiology | University of Rochester Medical Center, Rochester, NY, United States |
Area:
Biophysics of iGluRs and ASICs, pharmacologyWebsite:
macleanlab.netGoogle:
"David MacLean"Mean distance: 16.58 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| John F. MacDonald | research assistant | 2004-2005 | University of Toronto |
| Derek Bowie | grad student | 2005-2011 | McGill |
| Vasanthi Jayaraman | post-doc | University of Texas-Houston Medical School |
BETA: Related publications
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Publications
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| Durham RJ, Paudyal N, Carrillo E, et al. (2020) Conformational spread and dynamics in allostery of NMDA receptors. Proceedings of the National Academy of Sciences of the United States of America |
| Carrillo E, Shaikh SA, Berka V, et al. (2019) Mechanism of modulation of AMPA receptors by TARP-γ8. The Journal of General Physiology |
| MacLean DM, Durham RJ, Jayaraman V. (2018) Mapping the Conformational Landscape of Glutamate Receptors Using Single Molecule FRET. Trends in Neurosciences |
| Chen J, Li L, Chen SR, et al. (2018) The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions. Cell Reports. 22: 2307-2321 |
| Dolino DM, Chatterjee S, MacLean DM, et al. (2017) The structure-energy landscape of NMDA receptor gating. Nature Chemical Biology |
| Coombs ID, MacLean DM, Jayaraman V, et al. (2017) Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation. Cell Reports. 20: 1123-1135 |
| MacLean DM, Jayaraman V. (2017) Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive. Proceedings of the National Academy of Sciences of the United States of America |
| Vitrac H, MacLean DM, Karlstaedt A, et al. (2016) Dynamic lipid-dependent modulation of protein topology by post-translational phosphorylation. The Journal of Biological Chemistry |
| Shaikh SA, Dolino DM, Lee G, et al. (2016) Stargazin Modulation of AMPA Receptors. Cell Reports. 17: 328-335 |
| MacLean DM, Jayaraman V. (2016) Acid sensing ion channels are tuned to follow high frequency stimuli. The Journal of Physiology |