Paul K. Cheung, Ph.D.

Affiliations: 
2004 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Microbiology Biology
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"Paul Cheung"

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Decheng Yang grad student 2004 UBC
 (Specific protein interactions with the 5'- and 3'-untranslated regions of coxsackievirus B3 RNA.)
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Publications

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Cheung P, Lim T, Yuan J, et al. (2007) Specific interaction of HeLa cell proteins with coxsackievirus B3 3'UTR: La autoantigen binds the 3' and 5'UTR independently of the poly(A) tail. Cellular Microbiology. 9: 1705-15
Chau DH, Yuan J, Zhang H, et al. (2007) Coxsackievirus B3 proteases 2A and 3C induce apoptotic cell death through mitochondrial injury and cleavage of eIF4GI but not DAP5/p97/NAT1. Apoptosis : An International Journal On Programmed Cell Death. 12: 513-24
Cheung PK, Yuan J, Zhang HM, et al. (2005) Specific interactions of mouse organ proteins with the 5'untranslated region of coxsackievirus B3: potential determinants of viral tissue tropism. Journal of Medical Virology. 77: 414-24
Zhang HM, Yuan J, Cheung P, et al. (2005) Gamma interferon-inducible protein 10 induces HeLa cell apoptosis through a p53-dependent pathway initiated by suppression of human papillomavirus type 18 E6 and E7 expression. Molecular and Cellular Biology. 25: 6247-58
Yuan J, Cheung PK, Zhang HM, et al. (2005) Inhibition of coxsackievirus B3 replication by small interfering RNAs requires perfect sequence match in the central region of the viral positive strand. Journal of Virology. 79: 2151-9
Yuan J, Chen Z, Cheung P, et al. (2005) Nucleic acid-based gene-silencing molecules as potential antiviral therapeutics Drug Design Reviews - Online. 2: 323-333
Choy JC, Hung VH, Hunter AL, et al. (2004) Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 2245-50
Yuan J, Cheung PK, Zhang H, et al. (2004) A phosphorothioate antisense oligodeoxynucleotide specifically inhibits coxsackievirus B3 replication in cardiomyocytes and mouse hearts. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 703-14
Carthy CM, Yanagawa B, Luo H, et al. (2003) Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection. Virology. 313: 147-57
Zhang HM, Yuan J, Cheung P, et al. (2003) Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication. The Journal of Biological Chemistry. 278: 33011-9
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