Lawrence H. Uricchio, Ph.D.

Affiliations: 
2014 Biological and Medical Informatics University of California, San Francisco, San Francisco, CA 
Area:
Genetics, Bioinformatics Biology
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"Lawrence Uricchio"

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Ryan D. Hernandez grad student 2014 UCSF
 (Models and forward simulations of selection, human demography, and complex traits.)
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Publications

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Ebel ER, Uricchio LH, Petrov DA, et al. (2022) Revisiting the malaria hypothesis: accounting for polygenicity and pleiotropy. Trends in Parasitology
Hernandez RD, Uricchio LH, Hartman K, et al. (2019) Ultrarare variants drive substantial cis heritability of human gene expression. Nature Genetics. 51: 1349-1355
Uricchio LH. (2019) Evolutionary perspectives on polygenic selection, missing heritability, and GWAS. Human Genetics
Uricchio LH, Petrov DA, Enard D. (2019) Exploiting selection at linked sites to infer the rate and strength of adaptation. Nature Ecology & Evolution
Uricchio LH, Kitano HC, Gusev A, et al. (2019) An evolutionary compass for detecting signals of polygenic selection and mutational bias. Evolution Letters. 3: 69-79
Gignoux CR, Torgerson DG, Pino-Yanes M, et al. (2018) An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos. The Journal of Allergy and Clinical Immunology
Uricchio LH, Zaitlen NA, Ye CJ, et al. (2016) Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants. Genome Research
Uricchio LH, Torres R, Witte JS, et al. (2015) Population genetic simulations of complex phenotypes with implications for rare variant association tests. Genetic Epidemiology. 39: 35-44
Uricchio LH, Hernandez RD. (2014) Robust forward simulations of recurrent hitchhiking. Genetics. 197: 221-36
Maher MC, Uricchio LH, Torgerson DG, et al. (2012) Population genetics of rare variants and complex diseases. Human Heredity. 74: 118-28
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