Yasong Lu, Ph.D.
Affiliations: | 2006 | Colorado State University, Fort Collins, CO |
Area:
ToxicologyGoogle:
"Yasong Lu"Mean distance: 26716.5
Parents
Sign in to add mentor| Raymond K. Yang | grad student | 2006 | Colorado State | |
| (Application of physiologically based pharmacokinetic /pharmacodynamic (PBPK/PD) model in studying the carcinogenic potential of hexacholorobenzene, PCB 126, and their mixture.) | ||||
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| Karelina T, Demin O, Nicholas T, et al. (2017) A translational systems pharmacology model for Aβ kinetics in mouse, monkey, and human. Cpt: Pharmacometrics & Systems Pharmacology |
| Lu Y, Barton HA, Leung L, et al. (2013) Cerebrospinal fluid β-Amyloid turnover in the mouse, dog, monkey and human evaluated by systematic quantitative analyses. Neuro-Degenerative Diseases. 12: 36-50 |
| Hajos-Korcsok E, Nolan C, Robshaw A, et al. (2013) Cross-species analysis of cerebrospinal fluid (CSF) beta-amyloid reductions by the BACE1 inhibitor PF-05297909 indicates species differences in PK/PD relationships: Relevance to clinical translation Alzheimers & Dementia. 9: 300 |
| Nolan C, Atchison K, Pustilnik L, et al. (2013) Clinical gamma-secretase inhibitors (GSIs) alter beta-amyloid 40/42 ratio in brain and show CSF beta-amyloid rebound in vivo Alzheimers & Dementia. 9 |
| Nolan C, Atchison K, Robshaw A, et al. (2013) Evaluation of beta-amyloid-lowering efficacy of a novel BACE1 inhibitor in multiple species Alzheimers & Dementia. 9: 806 |
| Lu Y. (2012) Integrating experimentation and quantitative modeling to enhance discovery of Beta amyloid lowering therapeutics for Alzheimer's disease. Frontiers in Pharmacology. 3: 177 |
| Lu Y, Riddell D, Hajos-Korcsok E, et al. (2012) Cerebrospinal fluid amyloid-β (Aβ) as an effect biomarker for brain Aβ lowering verified by quantitative preclinical analyses. The Journal of Pharmacology and Experimental Therapeutics. 342: 366-75 |
| Stepan AF, Subramanyam C, Efremov IV, et al. (2012) Application of the bicyclo[1.1.1]pentane motif as a nonclassical phenyl ring bioisostere in the design of a potent and orally active γ-secretase inhibitor. Journal of Medicinal Chemistry. 55: 3414-24 |
| Lu Y, Barton H, Nicholas T, et al. (2012) An updated Aβ systems kinetic model for mouse, monkey and human Alzheimers & Dementia. 8: 208 |
| Nicholas T, Barton H, Lu Y, et al. (2012) Beta-amyloid aggregation human systems pharmacology modeling: Development and application to pharmacological targets in Alzheimer's disease Alzheimers & Dementia. 8 |