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Kristoff T. Homan, Ph.D.

Affiliations: 
2010 Biological Sciences Purdue University, West Lafayette, IN, United States 
Area:
General Biophysics, Biochemistry
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Cynthia V. Stauffacher grad student 2010 Purdue
 (Identification and evaluation of inhibitors for the human cytoplasmic protein tyrosine phosphatase.)

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Publications

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Waldschmidt HV, Homan KT, Cato MC, et al. (2019) Correction to "Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine". Journal of Medicinal Chemistry
Waldschmidt HV, Homan KT, Cato MC, et al. (2017) Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. Journal of Medicinal Chemistry
Yang P, Homan KT, Li Y, et al. (2016) Effect of Lipid Composition on Membrane Orientation of the G protein-coupled Receptor Kinase 2-Gβ1γ2 Complex. Biochemistry
Waldschmidt HV, Homan KT, Cruz-Rodriguez O, et al. (2016) Structure-Based Design, Synthesis and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. Journal of Medicinal Chemistry
Inagaki S, Ghirlando R, Vishnivetskiy SA, et al. (2015) G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro. Biochemistry. 54: 4320-9
Homan KT, Waldschmidt HV, Glukhova A, et al. (2015) Crystal Structure of G Protein-Coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor. The Journal of Biological Chemistry
Azevedo AW, Doan T, Moaven H, et al. (2015) C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor. Elife. 4
Li L, Homan KT, Vishnivetskiy SA, et al. (2015) G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs). The Journal of Biological Chemistry. 290: 10775-90
Homan KT, Larimore KM, Elkins JM, et al. (2015) Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors. Acs Chemical Biology. 10: 310-9
Homan KT, Tesmer JJ. (2015) Molecular basis for small molecule inhibition of G protein-coupled receptor kinases. Acs Chemical Biology. 10: 246-56
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