John R. Woolfrey, Ph.D.
Affiliations: | 2000 | The University of Mississippi, USA |
Area:
Pharmaceutical Chemistry, PharmacyGoogle:
"John Woolfrey"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Mitchell Allen Avery | grad student | 2000 | The University of Mississippi | |
| (Rational design, synthesis, and biological evaluation of nonsteroidal antiprogestins.) | ||||
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Publications
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| Zhang P, Huang W, Wang L, et al. (2009) Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor. Bioorganic & Medicinal Chemistry Letters. 19: 2179-85 |
| Zhang P, Bao L, Zuckett JF, et al. (2004) Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors with improved functional activity. Bioorganic & Medicinal Chemistry Letters. 14: 989-93 |
| Avery MA, Woolfrey JR. (2003) Anti-Inflammatory Steroids Burger's Medicinal Chemistry and Drug Discovery. 747-854 |
| Avery MA, Alvim-Gaston M, Rodrigues CR, et al. (2002) Structure-activity relationships of the antimalarial agent artemisinin. 6. The development of predictive in vitro potency models using CoMFA and HQSAR methodologies. Journal of Medicinal Chemistry. 45: 292-303 |
| Avery MA, Alvim-Gaston M, Woolfrey JR. (1999) Synthesis and structure-activity relationships of peroxidic antimalarials based on artemisinin Advances in Medicinal Chemistry. 4: 125-217 |
| Woolfrey JR, Avery MA, Doweyko AM. (1998) Comparison of 3D quantitative structure-activity relationship methods: analysis of the in vitro antimalarial activity of 154 artemisinin analogues by hypothetical active-site lattice and comparative molecular field analysis. Journal of Computer-Aided Molecular Design. 12: 165-81 |