Jamie B. Towle-Weicksel, Ph.D.
Affiliations: | 2012 | Chemistry | Clark University, Worcester, MA, United States |
Area:
Biochemistry, Molecular BiologyGoogle:
"Jamie Towle-Weicksel"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| David L. Thurlow | grad student | 2012 | Clark University | |
| (A chimeric protein constructed from Bacteriophage T7 gp4 and a putative primase-helicase from Arabidopsos thaliana mitochondria.) | ||||
Children
Sign in to add trainee| Lisbeth Avalos-Irving | research assistant | Rhode Island College | |
| Corey M Thomas | research assistant | Rhode Island College | |
| Morgan Andrews | grad student | Rhode Island College | |
| Sydney Green | grad student | ||
| Ayden Mudd | grad student | Rhode Island College | |
| Jorge Victorino | grad student | Rhode Island College |
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Publications
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| Thomas C, Avalos-Irving L, Victorino J, et al. (2024) Melanoma-Derived DNA Polymerase Theta Variants Exhibit Altered DNA Polymerase Activity. Biochemistry |
| Thomas C, Avalos-Irving L, Victorino J, et al. (2023) Melanoma-derived DNA polymerase theta variants exhibit altered DNA polymerase activity. Biorxiv : the Preprint Server For Biology |
| Fijen C, Mahmoud MM, Kronenberg M, et al. (2020) Using single-molecule FRET to probe the nucleotide-dependent conformational landscape of Pol β-DNA complexes. The Journal of Biological Chemistry |
| Liptak C, Mahmoud MM, Eckenroth BE, et al. (2018) I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Research |
| Mahmoud MM, Schechter A, Alnajjar KS, et al. (2017) Defective Nucleotide Release by DNA Polymerase Beta Mutator Variant E288K is the Basis of Its Low Fidelity. Biochemistry |
| Eckenroth BE, Towle-Weicksel JB, Nemec AA, et al. (2017) Remote mutations induce functional changes in active site residues of human DNA polymerase beta. Biochemistry |
| Nemec AA, Bush KB, Towle-Weicksel JB, et al. (2016) Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer-associated R438W DNA Polymerase Lambda Protein. Molecular Cancer Research : McR |
| Towle-Weicksel JB, Dalal S, Sohl CD, et al. (2014) Fluorescence resonance energy transfer studies of DNA polymerase β the critical role of fingers domain movements and a novel non-covalent step During nucleotide selection Journal of Biological Chemistry. 289: 16541-16550 |
| Eckenroth BE, Towle-Weicksel JB, Sweasy JB, et al. (2013) The E295K cancer variant of human polymerase β favors the mismatch conformational pathway during nucleotide selection. The Journal of Biological Chemistry. 288: 34850-60 |