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Jamie B. Towle-Weicksel, Ph.D. - Publications

Affiliations: 
2012 Chemistry Clark University, Worcester, MA, United States 
Area:
Biochemistry, Molecular Biology
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Thomas C, Avalos-Irving L, Victorino J, Green S, Andrews M, Rodrigues N, Ebirim S, Mudd A, Towle-Weicksel JB. Melanoma-derived DNA polymerase theta variants exhibit altered DNA polymerase activity. Biorxiv : the Preprint Server For Biology. PMID 38014040 DOI: 10.1101/2023.11.14.566933  0.496
2020 Fijen C, Mahmoud MM, Kronenberg M, Kaup R, Fontana M, Towle-Weicksel JB, Sweasy JB, Hohlbein J. Using single-molecule FRET to probe the nucleotide-dependent conformational landscape of Pol β-DNA complexes. The Journal of Biological Chemistry. PMID 32385112 DOI: 10.1074/Jbc.Ra120.013049  0.519
2018 Liptak C, Mahmoud MM, Eckenroth BE, Moreno MV, East K, Alnajjar KS, Huang J, Towle-Weicksel JB, Doublié S, Loria JP, Sweasy JB. I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Research. PMID 30239932 DOI: 10.1093/Nar/Gky825  0.504
2017 Mahmoud MM, Schechter A, Alnajjar KS, Huang J, Towle-Weicksel JB, Eckenroth BE, Doublié S, Sweasy JB. Defective Nucleotide Release by DNA Polymerase Beta Mutator Variant E288K is the Basis of Its Low Fidelity. Biochemistry. PMID 28945359 DOI: 10.1021/Acs.Biochem.7B00869  0.544
2017 Eckenroth BE, Towle-Weicksel JB, Nemec AA, Murphy DL, Sweasy JB, Doublié S. Remote mutations induce functional changes in active site residues of human DNA polymerase beta. Biochemistry. PMID 28402631 DOI: 10.1021/Acs.Biochem.6B01287  0.437
2016 Nemec AA, Bush KB, Towle-Weicksel JB, Taylor BF, Schulz V, Weidhaas J, Tuck DP, Sweasy JB. Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer-associated R438W DNA Polymerase Lambda Protein. Molecular Cancer Research : McR. PMID 27621267 DOI: 10.1158/1541-7786.Mcr-16-0209  0.387
2014 Towle-Weicksel JB, Dalal S, Sohl CD, Doublie S, Anderson KS, Sweasy JB. Fluorescence resonance energy transfer studies of DNA polymerase β the critical role of fingers domain movements and a novel non-covalent step During nucleotide selection Journal of Biological Chemistry. 289: 16541-16550. PMID 24764311 DOI: 10.1074/Jbc.M114.561878  0.553
2013 Eckenroth BE, Towle-Weicksel JB, Sweasy JB, Doublié S. The E295K cancer variant of human polymerase β favors the mismatch conformational pathway during nucleotide selection. The Journal of Biological Chemistry. 288: 34850-60. PMID 24133209 DOI: 10.1074/Jbc.M113.510891  0.526
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