Sandra S. Wise, Ph.D.

Affiliations: 
2013 The University of Maine, Orono, ME, United States 
Area:
Toxicology, Molecular Biology, Biochemistry, Oncology
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Stephen C. Pelsue grad student 2013 University of Maine
 (Characterizing the role of chromosome instability in particulate hexavalent chromium-induced carcinogenesis.)
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Publications

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Lu H, Toyoda JH, Wise SS, et al. (2024) A whale of a tale: whale cells evade the driving mechanism for hexavalent Chromium-Induced chromosome instability. Toxicological Sciences : An Official Journal of the Society of Toxicology
Wise JTF, Lu H, Meaza I, et al. (2024) Prolonged Particulate Hexavalent Chromium Exposure Induces DNA Double-Strand Breaks and Inhibits Homologous Recombination Repair in Primary Rodent Lung Cells. Biological Trace Element Research
Meaza I, Williams AR, Lu H, et al. (2023) Prolonged particulate hexavalent chromium exposure induces RAD51 foci inhibition and cytoplasmic accumulation in immortalized and primary human lung bronchial epithelial cells. Toxicology and Applied Pharmacology. 479: 116711
Wise SS, Lu H, Speer RM, et al. (2022) Chromium distribution in an oropharyngeal aspiration model for hexavalent chromium in rats. Toxicology and Applied Pharmacology. 116294
Meaza I, Speer RM, Toyoda JH, et al. (2020) Prolonged exposure to particulate Cr(VI) is cytotoxic and genotoxic to fin whale cells. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 62: 126562
Wu J, Ferragut Cardoso AP, States VAR, et al. (2019) Overexpression of hsa-miR-186 induces chromosomal instability in arsenic-exposed human keratinocytes. Toxicology and Applied Pharmacology. 114614
Speer R, Wise SS, Croom-Perez T, et al. (2019) A comparison of particulate hexavalent chromium cytotoxicity and genotoxicity in human and leatherback sea turtle lung cells from a one environmental health perspective. Toxicology and Applied Pharmacology
Wise JP, Wise JTF, Wise CF, et al. (2018) Metal Levels in Whales from the Gulf of Maine: A One Environmental Health approach. Chemosphere. 216: 653-660
Poirier MC, Lair S, Michaud R, et al. (2018) Intestinal polycyclic aromatic hydrocarbon-DNA adducts in a population of beluga whales with high levels of gastrointestinal cancers. Environmental and Molecular Mutagenesis
Wise SS, Aboueissa AE, Martino J, et al. (2018) Hexavalent Chromium-Induced Chromosome Instability Drives Permanent and Heritable Numerical and Structural Changes and a DNA Repair-Deficient Phenotype. Cancer Research
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