James E. Darnell, Jr., M.D.
Affiliations: | 1961-1964 | Massachusetts Institute of Technology, Cambridge, MA, United States | |
1964-1967 | Albert Einstein College of Medicine, New York, New York, United States | ||
1967-1974 | Columbia University, New York, NY | ||
1974- | Rockefeller University, New York, NY, United States |
Area:
STATs, developmentWebsite:
https://www.rockefeller.edu/our-scientists/emeritus-faculty/865-james-e-darnell-jr/Google:
"James E. Darnell Jr."Bio:
http://www.nasonline.org/member-directory/members/56513.html
http://lab.rockefeller.edu/emeriti/darnell/
https://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=48191
https://www.rockefeller.edu/about/history/oral-history-project/interview-james-e-darnell-jr/
https://www.nationalmedals.org/laureates/james-e-darnell
Discovered hnRNA.
Mean distance: 13.78 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentorRobert J. Glaser | research assistant | 1955 | Washington University School of Medicine (ID Tree) |
Harry Eagle | post-doc | 1956-1960 | NIH |
François Jacob | post-doc | 1960-1961 | Institut Pasteur |
Children
Sign in to add traineeDaniel Lew | grad student | Rockefeller (Cell Biology Tree) | |
Ke Shuai | grad student | (Chemistry Tree) | |
Jonathan Warner | grad student | MIT | |
Eva Derman | grad student | 1976 | Columbia (Cell Biology Tree) |
Jeffrey M. Friedman | grad student | 1986 | Rockefeller |
Aurel Betz | grad student | 2001 | Rockefeller |
Xiaomin Chen | post-doc | Rockefeller (Chemistry Tree) | |
Ronald M. Evans | post-doc | Rockefeller | |
Uno Lindberg | post-doc | Albert Einstein | |
Klaus Scherrer | post-doc | MIT | |
Christian Schindler | post-doc | Rockefeller (Microtree) | |
Ruy Soeiro | post-doc | Albert Einstein | |
Hermona Soreq | post-doc | Rockefeller | |
Michael C. Wilson | post-doc | University of New Mexico, Albuquerque | |
David Baltimore | post-doc | 1963-1964 | MIT (Chemistry Tree) |
B Edward H. Maden | post-doc | 1967-1969 | Albert Einstein (Chemistry Tree) |
Linda L. Walling | post-doc | 1980-1981 | Rockefeller (Cell Biology Tree) |
Xin-Yuan Fu | post-doc | 1988-1991 | Rockefeller |
Sheldon Penman | research scientist | MIT |
BETA: Related publications
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Publications
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Ke S, Alemu EA, Mertens C, et al. (2015) A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes & Development |
Schindler C, Shuai K, Prezioso VR, et al. (2011) Pillars article: Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science. 1992. 257: 809-813. Journal of Immunology (Baltimore, Md. : 1950). 187: 5489-94 |
Betz A, Ryoo HD, Steller H, et al. (2008) STAT92E is a positive regulator of Drosophila inhibitor of apoptosis 1 (DIAP/1) and protects against radiation-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 13805-10 |
Ginsberg M, Czeko E, Müller P, et al. (2007) Amino acid residues required for physical and cooperative transcriptional interaction of STAT3 and AP-1 proteins c-Jun and c-Fos. Molecular and Cellular Biology. 27: 6300-8 |
Mertens C, Zhong M, Krishnaraj R, et al. (2006) Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain. Genes & Development. 20: 3372-81 |
Betz A, Darnell JE. (2006) A Hopscotch-chromatin connection. Nature Genetics. 38: 977-9 |
Mao X, Ren Z, Parker GN, et al. (2005) Structural bases of unphosphorylated STAT1 association and receptor binding. Molecular Cell. 17: 761-71 |
Zhong M, Henriksen MA, Takeuchi K, et al. (2005) Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle. Proceedings of the National Academy of Sciences of the United States of America. 102: 3966-71 |
Chen X, Bhandari R, Vinkemeier U, et al. (2003) A reinterpretation of the dimerization interface of the N-terminal domains of STATs. Protein Science : a Publication of the Protein Society. 12: 361-5 |
Henriksen MA, Betz A, Fuccillo MV, et al. (2002) Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site. Genes & Development. 16: 2379-89 |