Geoffrey Chang

Affiliations: 
Biology University of California, San Diego, La Jolla, CA 
Area:
Molecular Biology, General Biophysics, Biochemistry
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"Geoffrey Chang"
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Collaborators

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Amro M. Hamdoun collaborator 2010- UCSD (Neurotree)
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Publications

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Nicklisch SCT, Pouv AK, Rees SD, et al. (2021) Transporter-interfering chemicals inhibit P-glycoprotein of yellowfin tuna (Thunnus albacares). Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 109101
Thomas C, Aller SG, Beis K, et al. (2020) Structural and functional diversity calls for a new classification of ABC transporters. Febs Letters
Maity K, Heumann JM, McGrath AP, et al. (2020) cryo-EM Structure of Rice OSCA1.2 Elucidates the Mechanical Basis of Membrane Hyperosmolality Gating in Plants Biophysical Journal. 118: 211a
Kopcho N, Chang G, Komives EA. (2019) Dynamics of ABC Transporter P-glycoprotein in Three Conformational States. Scientific Reports. 9: 15092
Kalogriopoulos NA, Rees SD, Ngo T, et al. (2019) Structural basis for GPCR-independent activation of heterotrimeric Gi proteins. Proceedings of the National Academy of Sciences of the United States of America
Schrankel CS, Gökirmak T, Lee CW, et al. (2019) Generation, expression and utilization of single-domain antibodies for in vivo protein localization and manipulation in sea urchin embryos. Methods in Cell Biology. 151: 353-376
Maity K, Heumann JM, McGrath AP, et al. (2019) Cryo-EM structure of OSCA1.2 fromOryza sativaelucidates the mechanical basis of potential membrane hyperosmolality gating. Proceedings of the National Academy of Sciences of the United States of America. 116: 14309-14318
Doshi R, McGrath AP, Piñeros M, et al. (2017) Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor. Scientific Reports. 7: 17996
Nicklisch SC, Rees SD, McGrath AP, et al. (2016) Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Science Advances. 2: e1600001
He X, Garza D, Nigam SK, et al. (2016) Multispecific Organic Cation Transporter 1 (OCT1) from Bos taurus Has High Affinity and Slow Binding Kinetics towards Prostaglandin E2. Plos One. 11: e0152969
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