Chad A. Lerner, Ph.D.

Affiliations: 
2012 Pathology Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Genetics
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"Chad Lerner"
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Christian Sell grad student 2012 Drexel Medical School
 (Lifespan mechanisms: A role for mitochondrial homeostasis controlled by insulin like signaling.)
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Publications

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Labbé K, Mookerjee S, Le Vasseur M, et al. (2021) The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis. The Journal of Cell Biology. 220
Lerner CA, Lei W, Sundar IK, et al. (2016) Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury. Frontiers in Pharmacology. 7: 391
Ahmad T, Sundar IK, Tormos AM, et al. (2016) Shelterin TPP1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirt1 Deacetylase in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory Cell and Molecular Biology
Lerner CA, Sundar IK, Rahman I. (2016) Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD. The International Journal of Biochemistry & Cell Biology
Lerner CA, Rutagarama P, Ahmad T, et al. (2016) Electronic cigarette aerosols and copper nanoparticles induce mitochondrial stress and promote DNA fragmentation in lung fibroblasts. Biochemical and Biophysical Research Communications
Ahmad T, Sundar IK, Lerner CA, et al. (2015) Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2912-29
Salmon AB, Lerner C, Ikeno Y, et al. (2015) Altered metabolism and resistance to obesity in long-lived mice producing reduced levels of IGF-I. American Journal of Physiology. Endocrinology and Metabolism. 308: E545-53
Crowe EP, Nacarelli T, Bitto A, et al. (2014) Detecting senescence: methods and approaches. Methods in Molecular Biology (Clifton, N.J.). 1170: 425-45
Bitto A, Crowe EP, Lerner C, et al. (2014) The senescence arrest program and the cell cycle. Methods in Molecular Biology (Clifton, N.J.). 1170: 145-54
Bitto A, Lerner CA, Nacarelli T, et al. (2014) P62/SQSTM1 at the interface of aging, autophagy, and disease. Age (Dordrecht, Netherlands). 36: 9626
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