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Chad A. Lerner, Ph.D. - Publications

Affiliations: 
2012 Pathology Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Genetics
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Labbé K, Mookerjee S, Le Vasseur M, Gibbs E, Lerner C, Nunnari J. The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis. The Journal of Cell Biology. 220. PMID 34586346 DOI: 10.1083/jcb.202103122  0.307
2016 Lerner CA, Lei W, Sundar IK, Rahman I. Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury. Frontiers in Pharmacology. 7: 391. PMID 27826243 DOI: 10.3389/Fphar.2016.00391  0.32
2016 Ahmad T, Sundar IK, Tormos AM, Lerner CA, Gerloff J, Yao H, Rahman I. Shelterin TPP1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirt1 Deacetylase in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory Cell and Molecular Biology. PMID 27559927 DOI: 10.1165/Rcmb.2016-0198Oc  0.345
2016 Lerner CA, Sundar IK, Rahman I. Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD. The International Journal of Biochemistry & Cell Biology. PMID 27474491 DOI: 10.1016/J.Biocel.2016.07.026  0.421
2016 Lerner CA, Rutagarama P, Ahmad T, Sundar IK, Elder A, Rahman I. Electronic cigarette aerosols and copper nanoparticles induce mitochondrial stress and promote DNA fragmentation in lung fibroblasts. Biochemical and Biophysical Research Communications. PMID 27343559 DOI: 10.1016/J.Bbrc.2016.06.109  0.367
2015 Ahmad T, Sundar IK, Lerner CA, Gerloff J, Tormos AM, Yao H, Rahman I. Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2912-29. PMID 25792665 DOI: 10.1096/Fj.14-268276  0.37
2015 Salmon AB, Lerner C, Ikeno Y, Motch Perrine SM, McCarter R, Sell C. Altered metabolism and resistance to obesity in long-lived mice producing reduced levels of IGF-I. American Journal of Physiology. Endocrinology and Metabolism. 308: E545-53. PMID 25648834 DOI: 10.1152/Ajpendo.00558.2014  0.513
2014 Crowe EP, Nacarelli T, Bitto A, Lerner C, Sell C, Torres C. Detecting senescence: methods and approaches. Methods in Molecular Biology (Clifton, N.J.). 1170: 425-45. PMID 24906328 DOI: 10.1007/978-1-4939-0888-2_23  0.612
2014 Bitto A, Crowe EP, Lerner C, Torres C, Sell C. The senescence arrest program and the cell cycle. Methods in Molecular Biology (Clifton, N.J.). 1170: 145-54. PMID 24906313 DOI: 10.1007/978-1-4939-0888-2_8  0.645
2014 Bitto A, Lerner CA, Nacarelli T, Crowe E, Torres C, Sell C. P62/SQSTM1 at the interface of aging, autophagy, and disease. Age (Dordrecht, Netherlands). 36: 9626. PMID 24557832 DOI: 10.1007/S11357-014-9626-3  0.638
2014 Lorenzini A, Salmon AB, Lerner C, Torres C, Ikeno Y, Motch S, McCarter R, Sell C. Mice producing reduced levels of insulin-like growth factor type 1 display an increase in maximum, but not mean, life span. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 410-9. PMID 23873963 DOI: 10.1093/Gerona/Glt108  0.525
2013 Lerner C, Bitto A, Pulliam D, Nacarelli T, Konigsberg M, Van Remmen H, Torres C, Sell C. Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts. Aging Cell. 12: 966-77. PMID 23795962 DOI: 10.1111/Acel.12122  0.677
2013 Pirrone V, Libon DJ, Sell C, Lerner CA, Nonnemacher MR, Wigdahl B. Impact of age on markers of HIV-1 disease. Future Virology. 8: 81-101. PMID 23596462 DOI: 10.2217/Fvl.12.127  0.493
2013 Bitto A, Lerner CA, Van Remmen H, Konigsberg M, Pulliam D, Torres C, Sell C. Rapamycin improves mitochondrial homeostasis and delays the onset of senescence by altering p62/SQSTM1 dynamics Experimental Gerontology. 48: 692-693. DOI: 10.1016/J.Exger.2013.05.035  0.629
2013 Lerner C, Bitto A, Torres C, Sell C. Enhanced autophagy drives coordinate expression in nuclear and mitochondrial genomes Experimental Gerontology. 48: 686. DOI: 10.1016/J.Exger.2013.05.015  0.647
2011 Fink LS, Roell M, Caiazza E, Lerner C, Stamato T, Hrelia S, Lorenzini A, Sell C. 53BP1 contributes to a robust genomic stability in human fibroblasts. Aging. 3: 836-45. PMID 21931182  0.677
2011 Lerner C, Bitto A, Torres C, Sell C. IGF-I deficient mice show enhanced autophagy and increased mitochondrial content Experimental Gerontology. 46: 211-212. DOI: 10.1016/J.Exger.2010.11.023  0.664
2011 Bitto A, Lerner CA, Perez VE, Torres C, Sell C. IGF-I signaling affects long-term viability of primary human fibroblasts by impairing mitophagy of dysfunctional mitochondria Experimental Gerontology. 46: 209. DOI: 10.1016/J.Exger.2010.11.016  0.644
2010 Fink LS, Lerner CA, Torres PF, Sell C. Ku80 facilitates chromatin binding of the telomere binding protein, TRF2. Cell Cycle (Georgetown, Tex.). 9: 3798-806. PMID 20890109 DOI: 10.4161/Cc.9.18.13129  0.67
2010 Bitto A, Lerner C, Torres C, Roell M, Malaguti M, Perez V, Lorenzini A, Hrelia S, Ikeno Y, Matzko ME, McCarter R, Sell C. Long-term IGF-I exposure decreases autophagy and cell viability. Plos One. 5: e12592. PMID 20830296 DOI: 10.1371/Journal.Pone.0012592  0.683
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