Christopher A. Del Negro, Ph.D.
Affiliations: | Applied Science | College of William and Mary, Williamsburg, VA |
Area:
Respiration, NeurophsiologyWebsite:
http://people.wm.edu/~cadeln/Google:
"Christopher A. Del Negro"Bio:
I am a systems neuroscientist interested in mechanisms of rhythm and pattern generation in the CNS. My research examines the neural origins of breathing in particular.
Mean distance: 15.01 (cluster 17)
Children
Sign in to add trainee| Ryland W. Pace | grad student | 2004-2007 | William and Mary |
| John A. Hayes | grad student | 2003-2009 | William and Mary |
| Maria Cristina Picardo | grad student | 2008-2012 | William and Mary |
| Xueying Wang | grad student | 2008-2012 | William and Mary |
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Publications
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| Borrus DS, Stettler MK, Grover CJ, et al. (2024) Inspiratory and sigh breathing rhythms depend on distinct cellular signalling mechanisms in the preBötzinger complex. The Journal of Physiology. 602: 809-834 |
| da Silva CA, Grover CJ, Picardo MCD, et al. (2023) Role of Na1.6-mediated persistent sodium current and bursting-pacemaker properties in breathing rhythm generation. Cell Reports. 42: 113000 |
| David CK, Sugimura YK, Kallurkar PS, et al. (2022) Single cell transcriptome sequencing of inspiratory neurons of the preBötzinger complex in neonatal mice. Scientific Data. 9: 457 |
| Kallurkar PS, Picardo MCD, Sugimura YK, et al. (2022) Transcriptomes of electrophysiologically recorded Dbx1-derived respiratory neurons of the preBötzinger complex in neonatal mice. Scientific Reports. 12: 2923 |
| Revill AL, Katzell A, Del Negro CA, et al. (2021) KCNQ Current Contributes to Inspiratory Burst Termination in the Pre-Bötzinger Complex of Neonatal Rats . Frontiers in Physiology. 12: 626470 |
| Borrus DS, Grover C, Conradi Smith GD, et al. (2020) Role of synaptic inhibition in the coupling of the respiratory rhythms that underlie eupnea and sigh behaviors. Eneuro |
| Kallurkar PS, Grover C, Picardo MCD, et al. (2019) Evaluating the burstlet theory of inspiratory rhythm and pattern generation. Eneuro |
| Picardo MCD, Sugimura YK, Dorst KE, et al. (2019) Trpm4 ion channels in pre-Bötzinger complex interneurons are essential for breathing motor pattern but not rhythm. Plos Biology. 17: e2006094 |
| Vann NC, Pham FD, Dorst KE, et al. (2018) Dbx1 Pre-Bötzinger Complex Interneurons Comprise the Core Inspiratory Oscillator for Breathing in Unanesthetized Adult Mice. Eneuro. 5 |
| Del Negro CA, Funk GD, Feldman JL. (2018) Breathing matters. Nature Reviews. Neuroscience |