Emily Brook Pratt

Affiliations: 
Oregon Health and Science University, Portland, OR 
Area:
Neuroscience, KATP
Google:
"Emily Pratt"
Mean distance: 19.47 (cluster 11)
 
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Publications

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Zhou Q, Pratt EB, Shyng SL. (2013) Engineered Kir6.2 mutations that correct the trafficking defect of K(ATP) channels caused by specific SUR1 mutations. Channels (Austin, Tex.). 7: 313-7
Pratt EB, Zhou Q, Gay JW, et al. (2012) Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels. The Journal of General Physiology. 140: 175-87
Shyng SL, Bushman JD, Pratt EB, et al. (2012) Molecular defects of ATP-sensitive potassium channels in congenital hyperinsulinism Monogenic Hyperinsulinemic Hypoglycemia Disorders. 21: 30-42
Pratt EB, Shyng SL. (2011) ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity. Channels (Austin, Tex.). 5: 314-9
Pratt EB, Tewson P, Bruederle CE, et al. (2011) N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2. The Journal of General Physiology. 137: 299-314
Pratt EB, Shyng SL. (2011) ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP 2 sensitivity Channels. 5
Yan FF, Pratt EB, Chen PC, et al. (2010) Role of Hsp90 in biogenesis of the beta-cell ATP-sensitive potassium channel complex. Molecular Biology of the Cell. 21: 1945-54
Pratt EB, Tewson P, Shyng S. (2010) Sulfonylurea Receptor Transmembrane Domain Zero Mutations that Disrupt Full Length and Minimal ATP-Sensitive Potassium Channel Properties Biophysical Journal. 98: 699a
Fu Y, Tian W, Pratt EB, et al. (2009) Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion. Plos One. 4: e5679
Pratt EB, Yan FF, Gay JW, et al. (2009) Sulfonylurea receptor 1 mutations that cause opposite insulin secretion defects with chemical chaperone exposure. The Journal of Biological Chemistry. 284: 7951-9
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