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Emily Brook Pratt - Publications

Affiliations: 
Oregon Health and Science University, Portland, OR 
Area:
Neuroscience, KATP
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Zhou Q, Pratt EB, Shyng SL. Engineered Kir6.2 mutations that correct the trafficking defect of K(ATP) channels caused by specific SUR1 mutations. Channels (Austin, Tex.). 7: 313-7. PMID 23695995 DOI: 10.4161/Chan.25003  0.745
2012 Pratt EB, Zhou Q, Gay JW, Shyng SL. Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels. The Journal of General Physiology. 140: 175-87. PMID 22802363 DOI: 10.1085/Jgp.201210803  0.814
2012 Shyng SL, Bushman JD, Pratt EB, Zhou Q. Molecular defects of ATP-sensitive potassium channels in congenital hyperinsulinism Monogenic Hyperinsulinemic Hypoglycemia Disorders. 21: 30-42. DOI: 10.1159/000334485  0.699
2011 Pratt EB, Shyng SL. ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity. Channels (Austin, Tex.). 5: 314-9. PMID 21654216 DOI: 10.4161/Chan.5.4.16510  0.804
2011 Pratt EB, Tewson P, Bruederle CE, Skach WR, Shyng SL. N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2. The Journal of General Physiology. 137: 299-314. PMID 21321069 DOI: 10.1085/Jgp.201010557  0.803
2011 Pratt EB, Shyng SL. ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP 2 sensitivity Channels. 5.  0.77
2010 Yan FF, Pratt EB, Chen PC, Wang F, Skach WR, David LL, Shyng SL. Role of Hsp90 in biogenesis of the beta-cell ATP-sensitive potassium channel complex. Molecular Biology of the Cell. 21: 1945-54. PMID 20427569 DOI: 10.1091/Mbc.E10-02-0116  0.785
2010 Pratt EB, Tewson P, Shyng S. Sulfonylurea Receptor Transmembrane Domain Zero Mutations that Disrupt Full Length and Minimal ATP-Sensitive Potassium Channel Properties Biophysical Journal. 98: 699a. DOI: 10.1016/J.Bpj.2009.12.3838  0.783
2009 Fu Y, Tian W, Pratt EB, Dirling LB, Shyng SL, Meshul CK, Cohen DM. Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion. Plos One. 4: e5679. PMID 19479076 DOI: 10.1371/Journal.Pone.0005679  0.548
2009 Pratt EB, Yan FF, Gay JW, Stanley CA, Shyng SL. Sulfonylurea receptor 1 mutations that cause opposite insulin secretion defects with chemical chaperone exposure. The Journal of Biological Chemistry. 284: 7951-9. PMID 19151370 DOI: 10.1074/Jbc.M807012200  0.801
2006 Lin CW, Lin YW, Yan FF, Casey J, Kochhar M, Pratt EB, Shyng SL. Kir6.2 mutations associated with neonatal diabetes reduce expression of ATP-sensitive K+ channels: implications in disease mechanism and sulfonylurea therapy. Diabetes. 55: 1738-46. PMID 16731837 DOI: 10.2337/Db05-1571  0.796
2005 Pratt EB, Brink TS, Bergson P, Voigt MM, Cook SP. Use-dependent inhibition of P2X3 receptors by nanomolar agonist. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7359-65. PMID 16093386 DOI: 10.1523/Jneurosci.5189-04.2005  0.469
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