Aaron N. Chang, Ph.D.
Affiliations: | 2002 | Harvard University, Cambridge, MA, United States |
Area:
Genetics, Molecular Biology, Neuroscience BiologyGoogle:
"Aaron Chang"Mean distance: 35622
Parents
Sign in to add mentor| Stuart H. Orkin | grad student | 2002 | Harvard | |
| (Genetic dissection of the zinc finger transcription factor GATA-2 in mouse development.) | ||||
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Publications
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| Isoda T, Moore AJ, He Z, et al. (2017) Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 171: 103-119.e18 |
| Chen S, Miyazaki M, Fisch K, et al. (2016) Id3 Orchestrates Germinal Center B Cell Development. Molecular and Cellular Biology |
| Banno A, Garcia DA, van Baarsel ED, et al. (2016) Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition. Oncotarget |
| Bossen C, Murre CS, Chang AN, et al. (2015) The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth. Nature Immunology. 16: 775-84 |
| Miyazaki M, Miyazaki K, Chen S, et al. (2015) The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis. Genes & Development. 29: 409-25 |
| Miyazaki M, Miyazaki K, Chen S, et al. (2014) Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease. Nature Immunology. 15: 767-76 |
| Lim L, Balakrishnan A, Huskey N, et al. (2014) MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer. Hepatology (Baltimore, Md.). 59: 202-15 |
| Toyoshima M, Howie HL, Imakura M, et al. (2012) Functional genomics identifies therapeutic targets for MYC-driven cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 9545-50 |
| Chau BN, Xin C, Hartner J, et al. (2012) MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways. Science Translational Medicine. 4: 121ra18 |
| Rayner KJ, Sheedy FJ, Esau CC, et al. (2011) Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. The Journal of Clinical Investigation. 121: 2921-31 |