James R. Shoblock, Ph.D.

Affiliations: 
2003 Albany Medical College of Union University 
Area:
Neuroscience Biology
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"James Shoblock"
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Stanley D. Glick grad student 2003 Albany Medical College of Union University
 (Examination of the neurochemical and behavioral effects of methamphetamine and amphetamine on dopamine and glutamate in the nucleus accumbens and prefrontal cortex: Putative reasons for the greater popularity of methamphetamine and implications for treat)
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Publications

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Bonaventure P, Shelton J, Yun S, et al. (2015) Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia. The Journal of Pharmacology and Experimental Therapeutics. 354: 471-82
Lord B, Aluisio L, Shoblock JR, et al. (2014) Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432. The Journal of Pharmacology and Experimental Therapeutics. 351: 628-41
Aluisio L, Fraser I, Berdyyeva T, et al. (2014) Pharmacological or genetic orexin1 receptor inhibition attenuates MK-801 induced glutamate release in mouse cortex. Frontiers in Neuroscience. 8: 107
Winterdahl M, Audrain H, Landau AM, et al. (2014) PET brain imaging of neuropeptide Y2 receptors using N-11C-methyl-JNJ-31020028 in pigs. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 635-9
Bhattacharya A, Wang Q, Ao H, et al. (2013) Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567. British Journal of Pharmacology. 170: 624-40
Bonaventure P, Aluisio L, Shoblock J, et al. (2011) Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission. Plos One. 6: e20210
Shoblock JR, Welty N, Aluisio L, et al. (2011) Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement. Psychopharmacology. 215: 191-203
Galici R, Rezvani AH, Aluisio L, et al. (2011) JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats. Psychopharmacology. 214: 829-41
Shoblock JR, Welty N, Nepomuceno D, et al. (2010) In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor. Psychopharmacology. 208: 265-77
Welty N, Shoblock JR. (2009) The effects of thioperamide on extracellular levels of glutamate and GABA in the rat prefrontal cortex. Psychopharmacology. 207: 433-8
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