Anil Purohit, Ph.D.

Affiliations: 
2003 Albany Medical College of Union University 
Area:
Pharmacology, Neuroscience Biology, Mental Health
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"Anil Purohit"
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Milt Teitler grad student 2003 Albany Medical College of Union University
 (Inverse agonist activity of antipsychotic drugs at constitutively active mutant human 5-HT(6) and 5-HT(7) serotonin receptors.)
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Publications

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Purohit A, Rokita AG, Guan X, et al. (2013) Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation. 128: 1748-57
Gao Z, Rasmussen TP, Li Y, et al. (2013) Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate. Circulation Research. 112: 309-17
Swaminathan PD, Purohit A, Hund TJ, et al. (2012) Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias. Circulation Research. 110: 1661-77
Swaminathan PD, Purohit A, Soni S, et al. (2011) Oxidized CaMKII causes cardiac sinus node dysfunction in mice. The Journal of Clinical Investigation. 121: 3277-88
Thiel WH, Chen B, Hund TJ, et al. (2008) Proarrhythmic defects in Timothy syndrome require calmodulin kinase II. Circulation. 118: 2225-34
Purohit A, Smith C, Herrick-Davis K, et al. (2005) Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs. Psychopharmacology. 179: 461-9
Glennon RA, Daoud MK, Dukat MS, et al. (2003) Arylguanidine and arylbiguanide binding at 5-HT3 serotonin receptors: A QSAR study Bioorganic and Medicinal Chemistry. 11: 4449-4454
Khorana N, Smith C, Herrick-Davis K, et al. (2003) Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors. Journal of Medicinal Chemistry. 46: 3930-7
Rahman AA, Daoud MK, Dukat M, et al. (2003) Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-chlorophenylbiguanide (mCPBG) and meta-chlorophenylguanidine (mCPG). Bioorganic & Medicinal Chemistry Letters. 13: 1119-23
Khorana N, Purohit A, Herrick-Davis K, et al. (2003) gamma-Carbolines: binding at 5-HT5A serotonin receptors. Bioorganic & Medicinal Chemistry. 11: 717-22
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