Ramin Shiekhattar

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Neuroscience Biology
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"Ramin Shiekhattar"
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Children

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Orr G. Barak grad student 2004 Penn
Jessica A. Norman grad student 2006 Penn
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Publications

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Dokaneheifard S, Gomes Dos Santos H, Valencia MG, et al. (2023) BRAT1 associates with INTS11/INTS9 heterodimer to regulate key neurodevelopmental genes. Biorxiv : the Preprint Server For Biology
Morgan M, Shiekhattar R, Shilatifard A, et al. (2022) It's a DoG-eat-DoG world-altered transcriptional mechanisms drive downstream-of-gene (DoG) transcript production. Molecular Cell. 82: 1981-1991
Shersher E, Lahiry M, Alvarez-Trotta A, et al. (2021) NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis. Cell Communication and Signaling : Ccs. 19: 96
Sun G, Shvab A, Leclerc GJ, et al. (2021) Protein Kinase D-Dependent Downregulation Of Immediate Early Genes Through Class IIa Histone Deacetylases In Acute Lymphoblastic Leukemia. Molecular Cancer Research : McR
Kirstein N, Gomes Dos Santos H, Blumenthal E, et al. (2020) The Integrator complex at the crossroad of coding and noncoding RNA. Current Opinion in Cell Biology. 70: 37-43
Barra J, Gaidosh GS, Blumenthal E, et al. (2020) Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA . Science Advances. 6: eaaz9072
Beckedorff F, Blumenthal E, daSilva LF, et al. (2020) The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts. Cell Reports. 32: 107917
Aoi Y, Smith ER, Shah AP, et al. (2020) NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release. Molecular Cell
Xu Y, Man N, Karl D, et al. (2019) TAF1 plays a critical role in AML1-ETO driven leukemogenesis. Nature Communications. 10: 4925
Shvab A, Sun G, Li B, et al. (2019) Abstract 1289: AICAR inhibits protein kinase D1 activity leading to epigenetic downregulation of immediate early genes via the NF-kB pathway in acute lymphoblastic leukemia Cancer Research. 79: 1289-1289
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