Ramin Shiekhattar - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Neuroscience Biology

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Morgan M, Shiekhattar R, Shilatifard A, Lauberth SM. It's a DoG-eat-DoG world-altered transcriptional mechanisms drive downstream-of-gene (DoG) transcript production. Molecular Cell. 82: 1981-1991. PMID 35487209 DOI: 10.1016/j.molcel.2022.04.008  0.314
2021 Shersher E, Lahiry M, Alvarez-Trotta A, Diluvio G, Robbins DJ, Shiekhattar R, Capobianco AJ. NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis. Cell Communication and Signaling : Ccs. 19: 96. PMID 34551776 DOI: 10.1186/s12964-021-00776-1  0.367
2021 Sun G, Shvab A, Leclerc GJ, Li B, Beckedorff F, Shiekhattar R, Barredo JC. Protein Kinase D-Dependent Downregulation Of Immediate Early Genes Through Class IIa Histone Deacetylases In Acute Lymphoblastic Leukemia. Molecular Cancer Research : McR. PMID 33980612 DOI: 10.1158/1541-7786.MCR-20-0808  0.307
2020 Kirstein N, Gomes Dos Santos H, Blumenthal E, Shiekhattar R. The Integrator complex at the crossroad of coding and noncoding RNA. Current Opinion in Cell Biology. 70: 37-43. PMID 33340967 DOI: 10.1016/j.ceb.2020.11.003  0.366
2020 Barra J, Gaidosh GS, Blumenthal E, Beckedorff F, Tayari MM, Kirstein N, Karakach TK, Jensen TH, Impens F, Gevaert K, Leucci E, Shiekhattar R, Marine JC. Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA . Science Advances. 6: eaaz9072. PMID 32923585 DOI: 10.1126/Sciadv.Aaz9072  0.403
2020 Beckedorff F, Blumenthal E, daSilva LF, Aoi Y, Cingaram PR, Yue J, Zhang A, Dokaneheifard S, Valencia MG, Gaidosh G, Shilatifard A, Shiekhattar R. The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts. Cell Reports. 32: 107917. PMID 32697989 DOI: 10.1016/J.Celrep.2020.107917  0.522
2020 Aoi Y, Smith ER, Shah AP, Rendleman EJ, Marshall SA, Woodfin AR, Chen FX, Shiekhattar R, Shilatifard A. NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release. Molecular Cell. PMID 32155413 DOI: 10.1016/J.Molcel.2020.02.014  0.403
2019 Xu Y, Man N, Karl D, Martinez C, Liu F, Sun J, Martinez CJ, Martin GM, Beckedorff F, Lai F, Yue J, Roisman A, Greenblatt S, Duffort S, Wang L, ... ... Shiekhattar R, et al. TAF1 plays a critical role in AML1-ETO driven leukemogenesis. Nature Communications. 10: 4925. PMID 31664040 DOI: 10.1038/S41467-019-12735-Z  0.421
2019 Shvab A, Sun G, Li B, Beckedorff F, Leclerc GJ, Shiekhattar R, Barredo JC. Abstract 1289: AICAR inhibits protein kinase D1 activity leading to epigenetic downregulation of immediate early genes via the NF-kB pathway in acute lymphoblastic leukemia Cancer Research. 79: 1289-1289. DOI: 10.1158/1538-7445.Am2019-1289  0.397
2019 Huang H, Adelman E, Wade D, Gaidosh G, Shiekhattar R, Figueroa M. 2035 – AGE-RELATED DOWNREGULATION OF LMNA IMPACTS HUMAN HEMATOPOIETIC STEM CELL FUNCTION Experimental Hematology. 76: e1. DOI: 10.1016/J.Exphem.2019.09.004  0.361
2018 Chan HL, Beckedorff F, Zhang Y, Garcia-Huidobro J, Jiang H, Colaprico A, Bilbao D, Figueroa ME, LaCava J, Shiekhattar R, Morey L. Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms. Nature Communications. 9: 3377. PMID 30139998 DOI: 10.1038/S41467-018-05728-X  0.405
2018 Amaral PP, Leonardi T, Han N, Viré E, Gascoigne DK, Arias-Carrasco R, Büscher M, Pandolfini L, Zhang A, Pluchino S, Maracaja-Coutinho V, Nakaya HI, Hemberg M, Shiekhattar R, Enright AJ, et al. Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci. Genome Biology. 19: 32. PMID 29540241 DOI: 10.1186/S13059-018-1405-5  0.337
2018 Sun GC, Shvab AC, Li BC, Beckedorff FC, Leclerc GJ, Shiekhattar R, Barredo JC. Acadesine Elicits a Rapid Epigenetic Reprograming of Immediate Early Genes through the Protein Kinase D1 Pathway in Acute Lymphoblastic Leukemia Cells Undergoing Energy/Metabolic Stress Blood. 132: 1321-1321. DOI: 10.1182/Blood-2018-99-112678  0.398
2017 Yue J, Lai F, Beckedorff F, Zhang A, Pastori C, Shiekhattar R. Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs. Genes & Development. 31: 1809-1820. PMID 28982763 DOI: 10.1101/Gad.301697.117  0.394
2017 Chen FX, Xie P, Collings CK, Cao K, Aoi Y, Marshall SA, Rendleman EJ, Ugarenko M, Ozark PA, Zhang A, Shiekhattar R, Smith ER, Zhang MQ, Shilatifard A. PAF1 regulation of promoter-proximal pause release via enhancer activation. Science (New York, N.Y.). PMID 28860207 DOI: 10.1126/Science.Aan3269  0.382
2017 Bose DA, Donahue G, Reinberg D, Shiekhattar R, Bonasio R, Berger SL. RNA Binding to CBP Stimulates Histone Acetylation and Transcription. Cell. 168: 135-149.e22. PMID 28086087 DOI: 10.1016/J.Cell.2016.12.020  0.463
2016 Cheng G, Liu F, Asai T, Lai F, Man N, Xu H, Chen S, Greenblatt S, Hamard PJ, Ando K, Martinez C, Tadi M, Wang L, Xu M, Yang FC, ... Shiekhattar R, et al. Loss of p300 accelerates MDS-associated leukemogenesis. Leukemia. PMID 27881875 DOI: 10.1038/Leu.2016.347  0.351
2016 Yang M, Liang C, Swaminathan K, Herrlinger S, Lai F, Shiekhattar R, Chen JF. A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy. Science Advances. 2: e1601167. PMID 27617292 DOI: 10.1126/Sciadv.1601167  0.464
2016 Li N, Li Y, Lv J, Zheng X, Wen H, Shen H, Zhu G, Chen TY, Dhar SS, Kan PY, Wang Z, Shiekhattar R, Shi X, Lan F, Chen K, et al. ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes. Molecular Cell. PMID 27477906 DOI: 10.1016/J.Molcel.2016.06.035  0.449
2016 Lai F, Blumenthal E, Shiekhattar R. Detection and Analysis of Long Noncoding RNAs. Methods in Enzymology. 573: 421-444. PMID 27372765 DOI: 10.1016/Bs.Mie.2016.03.010  0.366
2016 Kim TK, Shiekhattar R. Diverse regulatory interactions of long noncoding RNAs. Current Opinion in Genetics & Development. 36: 73-82. PMID 27151434 DOI: 10.1016/J.Gde.2016.03.014  0.451
2016 Xu Y, Man N, Martinez C, Martinez C, Beckedorf F, Cheng G, Greenblatt SM, Wang L, Shiekhattar R, Nimer SD. TAFII250 Is Critical in AML1-ETO Mediated Leukemogenesis Blood. 128: 1520-1520. DOI: 10.1182/Blood.V128.22.1520.1520  0.42
2015 Kim TK, Shiekhattar R. Architectural and Functional Commonalities between Enhancers and Promoters. Cell. 162: 948-59. PMID 26317464 DOI: 10.1016/J.Cell.2015.08.008  0.442
2015 Lai F, Gardini A, Zhang A, Shiekhattar R. Integrator mediates the biogenesis of enhancer RNAs. Nature. 525: 399-403. PMID 26308897 DOI: 10.1038/Nature14906  0.468
2015 Chen FX, Woodfin AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A. PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II. Cell. PMID 26279188 DOI: 10.1016/J.Cell.2015.07.042  0.415
2015 Gardini A, Shiekhattar R. The many faces of long noncoding RNAs. The Febs Journal. 282: 1647-57. PMID 25303371 DOI: 10.1111/Febs.13101  0.35
2014 Bonasio R, Shiekhattar R. Regulation of transcription by long noncoding RNAs. Annual Review of Genetics. 48: 433-55. PMID 25251851 DOI: 10.1146/Annurev-Genet-120213-092323  0.445
2014 Gardini A, Baillat D, Cesaroni M, Hu D, Marinis JM, Wagner EJ, Lazar MA, Shilatifard A, Shiekhattar R. Integrator regulates transcriptional initiation and pause release following activation. Molecular Cell. 56: 128-39. PMID 25201415 DOI: 10.1016/J.Molcel.2014.08.004  0.449
2014 Rocha-Viegas L, Villa R, Gutierrez A, Iriondo O, Shiekhattar R, Di Croce L. Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia. Molecular and Cellular Biology. 34: 3765-75. PMID 25071154 DOI: 10.1128/Mcb.00839-14  0.484
2014 Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, et al. Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response. Cell Metabolism. 19: 952-66. PMID 24814484 DOI: 10.1016/J.Cmet.2014.04.004  0.395
2014 Gardini A, Baillat D, Cesaroni M, Shiekhattar R. Genome-wide analysis reveals a role for BRCA1 and PALB2 in transcriptional co-activation. The Embo Journal. 33: 890-905. PMID 24591564 DOI: 10.1002/Embj.201385567  0.355
2014 Lai F, Shiekhattar R. Where long noncoding RNAs meet DNA methylation. Cell Research. 24: 263-4. PMID 24481530 DOI: 10.1038/Cr.2014.13  0.403
2014 Lai F, Shiekhattar R. Enhancer RNAs: the new molecules of transcription. Current Opinion in Genetics & Development. 25: 38-42. PMID 24480293 DOI: 10.1016/J.Gde.2013.11.017  0.466
2014 Gardini A, Baillat D, Cesaroni M, Shiekhattar R. Erratum: Genome-wide analysis reveals a role for BRCA1 and PALB2 in transcriptional co-activation (EMBO Journal (2014) 33 (890-905) DOI:10.1002/embj.201385567) The Embo Journal. 33. DOI: 10.15252/Embj.201470080  0.351
2013 Shiekhattar R. PINTing for p53. Genome Biology. 14: 132. PMID 24079657 DOI: 10.1186/Gb-2013-14-9-132  0.316
2013 Shiekhattar R. Opening the Chromatin by eRNAs. Molecular Cell. 51: 557-8. PMID 24034693 DOI: 10.1016/J.Molcel.2013.08.033  0.405
2013 Ørom UA, Shiekhattar R. Long noncoding RNAs usher in a new era in the biology of enhancers. Cell. 154: 1190-3. PMID 24034243 DOI: 10.1016/J.Cell.2013.08.028  0.396
2013 Shiekhattar R. The Yin and Yang of enhancer-like RNAs. The Embo Journal. 32: 2533-4. PMID 23942236 DOI: 10.1038/Emboj.2013.185  0.313
2013 Lai F, Orom UA, Cesaroni M, Beringer M, Taatjes DJ, Blobel GA, Shiekhattar R. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature. 494: 497-501. PMID 23417068 DOI: 10.1038/Nature11884  0.53
2012 Baillat D, Gardini A, Cesaroni M, Shiekhattar R. Requirement for SNAPC1 in transcriptional responsiveness to diverse extracellular signals. Molecular and Cellular Biology. 32: 4642-50. PMID 22966203 DOI: 10.1128/Mcb.00906-12  0.476
2012 Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, Guernec G, Martin D, Merkel A, Knowles DG, Lagarde J, Veeravalli L, Ruan X, Ruan Y, Lassmann T, ... ... Shiekhattar R, et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Research. 22: 1775-89. PMID 22955988 DOI: 10.1101/Gr.132159.111  0.435
2012 Herz HM, Mohan M, Garrett AS, Miller C, Casto D, Zhang Y, Seidel C, Haug JS, Florens L, Washburn MP, Yamaguchi M, Shiekhattar R, Shilatifard A. Polycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila. Molecular and Cellular Biology. 32: 1683-93. PMID 22354997 DOI: 10.1128/Mcb.06503-11  0.529
2012 Shiekhattar R. Abstract IA6: Elucidation of enhancer-like RNAs Cancer Research. 72. DOI: 10.1158/1538-7445.Nonrna12-Ia6  0.408
2011 Orom UA, Shiekhattar R. Noncoding RNAs and enhancers: complications of a long-distance relationship. Trends in Genetics : Tig. 27: 433-9. PMID 21831473 DOI: 10.1016/J.Tig.2011.06.009  0.432
2011 Mejetta S, Morey L, Pascual G, Kuebler B, Mysliwiec MR, Lee Y, Shiekhattar R, Di Croce L, Benitah SA. Jarid2 regulates mouse epidermal stem cell activation and differentiation. The Embo Journal. 30: 3635-46. PMID 21811233 DOI: 10.1038/Emboj.2011.265  0.338
2011 Carré C, Shiekhattar R. Human GTPases associate with RNA polymerase II to mediate its nuclear import. Molecular and Cellular Biology. 31: 3953-62. PMID 21768307 DOI: 10.1128/Mcb.05442-11  0.427
2011 Ørom UA, Shiekhattar R. Long non-coding RNAs and enhancers. Current Opinion in Genetics & Development. 21: 194-8. PMID 21330130 DOI: 10.1016/J.Gde.2011.01.020  0.447
2011 Fortschegger K, Shiekhattar R. Plant homeodomain fingers form a helping hand for transcription. Epigenetics. 6: 4-8. PMID 20818169 DOI: 10.4161/Epi.6.1.13297  0.502
2010 Ørom UA, Derrien T, Guigo R, Shiekhattar R. Long noncoding RNAs as enhancers of gene expression Cold Spring Harbor Symposia On Quantitative Biology. 75: 325-331. PMID 21502407 DOI: 10.1101/Sqb.2010.75.058  0.435
2010 Ørom UA, Derrien T, Beringer M, Gumireddy K, Gardini A, Bussotti G, Lai F, Zytnicki M, Notredame C, Huang Q, Guigo R, Shiekhattar R. Long noncoding RNAs with enhancer-like function in human cells. Cell. 143: 46-58. PMID 20887892 DOI: 10.1016/J.Cell.2010.09.001  0.45
2010 Fortschegger K, de Graaf P, Outchkourov NS, van Schaik FM, Timmers HT, Shiekhattar R. PHF8 targets histone methylation and RNA polymerase II to activate transcription. Molecular and Cellular Biology. 30: 3286-98. PMID 20421419 DOI: 10.1128/Mcb.01520-09  0.512
2009 Baillat D, Shiekhattar R. Functional dissection of the human TNRC6 (GW182-related) family of proteins. Molecular and Cellular Biology. 29: 4144-55. PMID 19470757 DOI: 10.1128/Mcb.00380-09  0.406
2009 Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. An operational definition of epigenetics. Genes & Development. 23: 781-3. PMID 19339683 DOI: 10.1101/Gad.1787609  0.366
2008 Savas JN, Makusky A, Ottosen S, Baillat D, Then F, Krainc D, Shiekhattar R, Markey SP, Tanese N. Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies. Proceedings of the National Academy of Sciences of the United States of America. 105: 10820-5. PMID 18669659 DOI: 10.1073/Pnas.0800658105  0.42
2008 Messick TE, Russell NS, Iwata AJ, Sarachan KL, Shiekhattar R, Shanks JR, Reyes-Turcu FE, Wilkinson KD, Marmorstein R. Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein. The Journal of Biological Chemistry. 283: 11038-49. PMID 18270205 DOI: 10.1074/Jbc.M704398200  0.373
2008 Di Croce L, Shiekhattar R. Thrilling transcription through threonine phosphorylation. Nature Cell Biology. 10: 5-6. PMID 18172424 DOI: 10.1038/Ncb0108-5  0.42
2008 Smith ER, Lee MG, Winter B, Droz NM, Eissenberg JC, Shiekhattar R, Shilatifard A. Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Molecular and Cellular Biology. 28: 1041-6. PMID 18039863 DOI: 10.1128/Mcb.01504-07  0.446
2007 Ingvarsdottir K, Edwards C, Lee MG, Lee JS, Schultz DC, Shilatifard A, Shiekhattar R, Berger SL. Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Molecular and Cellular Biology. 27: 7856-64. PMID 17875926 DOI: 10.1128/Mcb.00801-07  0.442
2007 Huang J, Sengupta R, Espejo AB, Lee MG, Dorsey JA, Richter M, Opravil S, Shiekhattar R, Bedford MT, Jenuwein T, Berger SL. p53 is regulated by the lysine demethylase LSD1. Nature. 449: 105-8. PMID 17805299 DOI: 10.1038/Nature06092  0.45
2007 Lee MG, Villa R, Trojer P, Norman J, Yan KP, Reinberg D, Di Croce L, Shiekhattar R. Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science (New York, N.Y.). 318: 447-50. PMID 17761849 DOI: 10.1126/Science.1149042  0.704
2007 Shiekhattar R. Dicer finds a new partner in transcriptional gene silencing. Molecular Cell. 27: 519-20. PMID 17707223 DOI: 10.1016/J.Molcel.2007.08.005  0.432
2007 Kumaraswamy E, Shiekhattar R. Activation of BRCA1/BRCA2-associated helicase BACH1 is required for timely progression through S phase. Molecular and Cellular Biology. 27: 6733-41. PMID 17664283 DOI: 10.1128/Mcb.00961-07  0.328
2007 Kawahara Y, Zinshteyn B, Chendrimada TP, Shiekhattar R, Nishikura K. RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex. Embo Reports. 8: 763-9. PMID 17599088 DOI: 10.1038/Sj.Embor.7401011  0.321
2007 Chendrimada TP, Finn KJ, Ji X, Baillat D, Gregory RI, Liebhaber SA, Pasquinelli AE, Shiekhattar R. MicroRNA silencing through RISC recruitment of eIF6. Nature. 447: 823-8. PMID 17507929 DOI: 10.1038/Nature05841  0.396
2007 Zuccolo M, Alves A, Galy V, Bolhy S, Formstecher E, Racine V, Sibarita JB, Fukagawa T, Shiekhattar R, Yen T, Doye V. The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. The Embo Journal. 26: 1853-64. PMID 17363900 DOI: 10.1038/Sj.Emboj.7601642  0.425
2007 Eissenberg JC, Lee MG, Schneider J, Ilvarsonn A, Shiekhattar R, Shilatifard A. The trithorax-group gene in Drosophila little imaginal discs encodes a trimethylated histone H3 Lys4 demethylase. Nature Structural & Molecular Biology. 14: 344-6. PMID 17351630 DOI: 10.1038/Nsmb1217  0.46
2007 Lee MG, Norman J, Shilatifard A, Shiekhattar R. Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein. Cell. 128: 877-87. PMID 17320162 DOI: 10.1016/J.Cell.2007.02.004  0.728
2006 Lee MG, Wynder C, Norman J, Shiekhattar R. Isolation and characterization of histone H3 lysine 4 demethylase-containing complexes. Methods (San Diego, Calif.). 40: 327-30. PMID 17101444 DOI: 10.1016/J.Ymeth.2006.07.030  0.68
2006 Nicolas E, Lee MG, Hakimi MA, Cam HP, Grewal SI, Shiekhattar R. Fission yeast homologs of human histone H3 lysine 4 demethylase regulate a common set of genes with diverse functions. The Journal of Biological Chemistry. 281: 35983-8. PMID 16990277 DOI: 10.1074/Jbc.M606349200  0.557
2006 Gregory RI, Chendrimada TP, Shiekhattar R. MicroRNA biogenesis: isolation and characterization of the microprocessor complex. Methods in Molecular Biology (Clifton, N.J.). 342: 33-47. PMID 16957365 DOI: 10.1385/1-59745-123-1:33  0.341
2006 Lee MG, Wynder C, Bochar DA, Hakimi MA, Cooch N, Shiekhattar R. Functional interplay between histone demethylase and deacetylase enzymes. Molecular and Cellular Biology. 26: 6395-402. PMID 16914725 DOI: 10.1128/Mcb.00723-06  0.43
2006 Lee MG, Wynder C, Schmidt DM, McCafferty DG, Shiekhattar R. Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chemistry & Biology. 13: 563-7. PMID 16793513 DOI: 10.1016/J.Chembiol.2006.05.004  0.382
2006 Norman JA, Shiekhattar R. Analysis of Nedd8-associated polypeptides: a model for deciphering the pathway for ubiquitin-like modifications. Biochemistry. 45: 3014-9. PMID 16503656 DOI: 10.1021/Bi052435A  0.623
2006 Da G, Lenkart J, Zhao K, Shiekhattar R, Cairns BR, Marmorstein R. Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes. Proceedings of the National Academy of Sciences of the United States of America. 103: 2057-62. PMID 16461455 DOI: 10.1073/Pnas.0510949103  0.442
2006 Yang W, Chendrimada TP, Wang Q, Higuchi M, Seeburg PH, Shiekhattar R, Nishikura K. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nature Structural & Molecular Biology. 13: 13-21. PMID 16369484 DOI: 10.1038/Nsmb1041  0.327
2006 Ross DA, Hannenhalli S, Tobias JW, Cooch N, Shiekhattar R, Kadesch T. Functional analysis of Hes-1 in preadipocytes. Molecular Endocrinology (Baltimore, Md.). 20: 698-705. PMID 16282371 DOI: 10.1210/Me.2005-0325  0.442
2005 Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell. 123: 631-40. PMID 16271387 DOI: 10.1016/J.Cell.2005.10.022  0.347
2005 Baillat D, Hakimi MA, Näär AM, Shilatifard A, Cooch N, Shiekhattar R. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. Cell. 123: 265-76. PMID 16239144 DOI: 10.1016/J.Cell.2005.08.019  0.441
2005 Wynder C, Hakimi MA, Epstein JA, Shilatifard A, Shiekhattar R. Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation. Nature Cell Biology. 7: 1113-7. PMID 16227968 DOI: 10.1038/Ncb1312  0.461
2005 Lee MG, Wynder C, Cooch N, Shiekhattar R. An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature. 437: 432-5. PMID 16079794 DOI: 10.1038/Nature04021  0.549
2005 Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature. 436: 740-4. PMID 15973356 DOI: 10.1038/Nature03868  0.626
2005 Gregory RI, Shiekhattar R. MicroRNA biogenesis and cancer. Cancer Research. 65: 3509-12. PMID 15867338 DOI: 10.1158/0008-5472.Can-05-0298  0.353
2005 Guo S, Hakimi MA, Baillat D, Chen X, Farber MJ, Klein-Szanto AJ, Cooch NS, Godwin AK, Shiekhattar R. Linking transcriptional elongation and messenger RNA export to metastatic breast cancers. Cancer Research. 65: 3011-6. PMID 15833825 DOI: 10.1158/0008-5472.Can-04-3624  0.307
2005 Zhou J, Chau CM, Deng Z, Shiekhattar R, Spindler MP, Schepers A, Lieberman PM. Cell cycle regulation of chromatin at an origin of DNA replication. The Embo Journal. 24: 1406-17. PMID 15775975 DOI: 10.1038/Sj.Emboj.7600609  0.446
2005 Banting GS, Barak O, Ames TM, Burnham AC, Kardel MD, Cooch NS, Davidson CE, Godbout R, McDermid HE, Shiekhattar R. CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L. Human Molecular Genetics. 14: 513-24. PMID 15640247 DOI: 10.1093/Hmg/Ddi048  0.792
2004 Gregory RI, Shiekhattar R. Chromatin modifiers and carcinogenesis. Trends in Cell Biology. 14: 695-702. PMID 15564046 DOI: 10.1016/J.Tcb.2004.10.002  0.483
2004 Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R. The Microprocessor complex mediates the genesis of microRNAs. Nature. 432: 235-40. PMID 15531877 DOI: 10.1038/Nature03120  0.447
2004 Barak O, Lazzaro MA, Cooch NS, Picketts DJ, Shiekhattar R. A tissue-specific, naturally occurring human SNF2L variant inactivates chromatin remodeling. The Journal of Biological Chemistry. 279: 45130-8. PMID 15310751 DOI: 10.1074/Jbc.M406212200  0.753
2004 Tang J, Wu S, Liu H, Stratt R, Barak OG, Shiekhattar R, Picketts DJ, Yang X. A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein. The Journal of Biological Chemistry. 279: 20369-77. PMID 14990586 DOI: 10.1074/Jbc.M401321200  0.774
2004 Barak OG, Shiekhattar R. Preparation and assays for mammalian ISWI complexes. Methods in Enzymology. 377: 389-401. PMID 14979040 DOI: 10.1016/S0076-6879(03)77025-6  0.734
2003 Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R. Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. Molecular Cell. 12: 1087-99. PMID 14636569 DOI: 10.1016/S1097-2765(03)00424-6  0.426
2003 Barak O, Lazzaro MA, Lane WS, Speicher DW, Picketts DJ, Shiekhattar R. Isolation of human NURF: a regulator of Engrailed gene expression. The Embo Journal. 22: 6089-100. PMID 14609955 DOI: 10.1093/Emboj/Cdg582  0.775
2003 Cho DS, Yang W, Lee JT, Shiekhattar R, Murray JM, Nishikura K. Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA. The Journal of Biological Chemistry. 278: 17093-102. PMID 12618436 DOI: 10.1074/jbc.M213127200  0.337
2003 Hakimi MA, Dong Y, Lane WS, Speicher DW, Shiekhattar R. A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes. The Journal of Biological Chemistry. 278: 7234-9. PMID 12493763 DOI: 10.1074/Jbc.M208992200  0.517
2002 Hakimi MA, Bochar DA, Schmiesing JA, Dong Y, Barak OG, Speicher DW, Yokomori K, Shiekhattar R. A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature. 418: 994-8. PMID 12198550 DOI: 10.1038/Nature01024  0.775
2002 Hakimi MA, Speicher DW, Shiekhattar R. The motor protein kinesin-1 links neurofibromin and merlin in a common cellular pathway of neurofibromatosis. The Journal of Biological Chemistry. 277: 36909-12. PMID 12191989 DOI: 10.1074/Jbc.C200434200  0.342
2002 Hakimi MA, Bochar DA, Chenoweth J, Lane WS, Mandel G, Shiekhattar R. A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes. Proceedings of the National Academy of Sciences of the United States of America. 99: 7420-5. PMID 12032298 DOI: 10.1073/Pnas.112008599  0.559
2001 Lo WS, Duggan L, Emre NC, Belotserkovskya R, Lane WS, Shiekhattar R, Berger SL. Snf1--a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science (New York, N.Y.). 293: 1142-6. PMID 11498592 DOI: 10.1126/Science.1062322  0.477
2001 Marmorstein LY, Kinev AV, Chan GKT, Bochar DA, Beniya H, Epstein JA, Yen TJ, Shiekhattar R. A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression Cell. 104: 247-257. PMID 11207365 DOI: 10.1016/S0092-8674(01)00209-4  0.463
2000 Bochar DA, Wang L, Beniya H, Kinev A, Xue Y, Lane WS, Wang W, Kashanchi F, Shiekhattar R. BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer Cell. 102: 257-265. PMID 10943845 DOI: 10.1016/S0092-8674(00)00030-1  0.454
2000 Guenther MG, Lane WS, Fischle W, Verdin E, Lazar MA, Shiekhattar R. A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness. Genes & Development. 14: 1048-57. PMID 10809664  0.421
2000 Schang LM, Hwang GJ, Dynlacht BD, Speicher DW, Bantly A, Schaffer PA, Shilatifard A, Ge H, Shiekhattar R. Human PC4 is a substrate-specific inhibitor of RNA polymerase II phosphorylation. The Journal of Biological Chemistry. 275: 6071-4. PMID 10692395 DOI: 10.1074/Jbc.275.9.6071  0.329
2000 Bochar DA, Savard J, Wang W, Lafleur DW, Moore P, Côté J, Shiekhattar R. A family of chromatin remodeling factors related to Williams syndrome transcription factor Proceedings of the National Academy of Sciences of the United States of America. 97: 1038-1043. PMID 10655480 DOI: 10.1073/Pnas.97.3.1038  0.497
2000 Guenther MG, Lane WS, Fischle W, Verdin E, Lazar MA, Shiekhattar R. A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness. Genes & Development. 14: 1048-1057. DOI: 10.1101/Gad.14.9.1048  0.516
1999 Schmidt AE, Miller T, Schmidt SL, Shiekhattar R, Shilatifard A. Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II. The Journal of Biological Chemistry. 274: 21981-5. PMID 10419521 DOI: 10.1074/Jbc.274.31.21981  0.494
1999 Bochar DA, Pan ZQ, Knights R, Fisher RP, Shilatifard A, Shiekhattar R. Inhibition of transcription by the trimeric cyclin-dependent kinase 7 complex. The Journal of Biological Chemistry. 274: 13162-6. PMID 10224071 DOI: 10.1074/Jbc.274.19.13162  0.462
1999 Zerby D, Chen CJ, Poon E, Lee D, Shiekhattar R, Lieberman PM. The amino-terminal C/H1 domain of CREB binding protein mediates Zta transcriptional activation of latent Epstein-Barr virus Molecular and Cellular Biology. 19: 1617-1626. PMID 10022850 DOI: 10.1128/Mcb.19.3.1617  0.39
1998 Reinberg D, Orphanides G, Ebright R, Akoulitchev S, Carcamo J, Cho H, Cortes P, Drapkin R, Flores O, Ha I, Inostroza JA, Kim S, Kim TK, Kumar P, Lagrange T, ... ... Shiekhattar R, et al. The RNA polymerase II general transcription factors: Past, present, and future Cold Spring Harbor Symposia On Quantitative Biology. 63: 83-103. PMID 10384273 DOI: 10.1101/Sqb.1998.63.83  0.354
1996 Maldonado E, Shiekhattar R, Sheldon M, Cho H, Drapkin R, Rickert P, Leest E, Anderson CW, Linn S, Reinberg D. A human RNA polymerase II complex associated with SRB and DNA-repair proteins Nature. 381: 86-89. PMID 8609996 DOI: 10.1038/381086A0  0.472
1996 Maldonado E, Shiekhattar R, Sheldon M, Cho H, Drapkin R, Rickert P, Lees E, Anderson CW, Linn S, Reinberg D. Erratum: A human RNA polymerase II complex associated with SRB and DNA-repair proteins Nature. 384: 384-384. DOI: 10.1038/384384A0  0.408
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