Juan M. Schvartzman, Ph.D.
Affiliations: | 2004-2011 | Weill Cornell Medical College, New York, NY, United States | |
| 2004-2011 | Cancer Biology & Genetics | Sloan Kettering Institute, New York, NY, United States | |
| 2011-2014 | Internal Medicine | Montefiore Medical Center, New York, NY, United States | |
| 2014-2022 | Department of Medicine | Memorial Sloan Kettering Cancer Center, Rockville Centre, NY, United States | |
| 2015-2022 | Cancer Biology & Genetics | Sloan Kettering Institute, New York, NY, United States | |
| 2022- | Department of Medicine | Columbia College of Physicians and Surgeons |
Area:
Molecular Biology, OncologyWebsite:
http://schvartzmanlab.orgGoogle:
"Juan Schvartzman"Mean distance: 26716.5
Parents
Sign in to add mentor| Robert Benezra | grad student | 2004-2011 | Weill Cornell Medical College | |
| (Mad2 upregulation mediates the chromosome instability imparted by Rb pathway inhibition.) | ||||
| Craig B. Thompson | post-doc | 2015-2022 | Memorial Sloan Kettering Cancer Center (Chemistry Tree) | |
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Publications
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| Schvartzman JM, Reuter VP, Koche RP, et al. (2019) 2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation. Proceedings of the National Academy of Sciences of the United States of America |
| Schvartzman JM, Thompson CB, Finley LWS. (2018) Metabolic regulation of chromatin modifications and gene expression. The Journal of Cell Biology |
| Schvartzman JM, Duijf PH, Sotillo R, et al. (2011) Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition. Cancer Cell. 19: 701-14 |
| Sotillo R, Schvartzman JM, Socci ND, et al. (2010) Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal. Nature. 464: 436-40 |
| Schvartzman JM, Sotillo R, Benezra R. (2010) Mitotic chromosomal instability and cancer: mouse modelling of the human disease. Nature Reviews. Cancer. 10: 102-15 |
| Sotillo R, Schvartzman JM, Benezra R. (2009) Very CIN-ful: whole chromosome instability promotes tumor suppressor loss of heterozygosity. Cancer Cell. 16: 451-2 |
| Diaz-Rodríguez E, Sotillo R, Schvartzman JM, et al. (2008) Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 16719-24 |