Karlene A. Cimprich

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
DNA damage response
Website:
http://med.stanford.edu/profiles/Karlene_Cimprich/
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"Karlene Cimprich"
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SNBCP

Parents

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Elias James Corey grad student 1994 Harvard
 (The use of chiral oxazaborolidines for asymmetric synthesis)
Stuart L. Schreiber post-doc 1994-1997 Harvard

Children

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Stephan Hamperl grad student (Cell Biology Tree)
Ryan D. Bomgarden grad student 2005 Stanford
Tony S. Byun grad student 2005 Stanford
Patrick J. Lupardus grad student 2005 Stanford
Christina A. MacDougall grad student 2007 Stanford
Debbie J. Chang grad student 2009 Stanford
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Publications

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Crossley MP, Song C, Bocek MJ, et al. (2024) Author Correction: R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response. Nature
Bai G, Endres T, Kühbacher U, et al. (2023) HLTF Prevents G4 Accumulation and Promotes G4-induced Fork Slowing to Maintain Genome Stability. Biorxiv : the Preprint Server For Biology
Cimprich KA, Li GM, Demaria S, et al. (2023) The crosstalk between DNA repair and immune responses. Molecular Cell. 83: 3582-3587
Stoy H, Zwicky K, Kuster D, et al. (2023) Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids. Nature Structural & Molecular Biology. 30: 348-359
Crossley MP, Song C, Bocek MJ, et al. (2022) R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response. Nature
Crossley MP, Cimprich KA. (2022) Quantitative DNA-RNA Immunoprecipitation Sequencing with Spike-Ins. Methods in Molecular Biology (Clifton, N.J.). 2528: 381-410
Brickner JR, Garzon JL, Cimprich KA. (2022) Walking a tightrope: The complex balancing act of R-loops in genome stability. Molecular Cell
Crossley MP, Brickner JR, Song C, et al. (2021) Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA-DNA hybrid imaging. The Journal of Cell Biology. 220
Crossley MP, Bocek MJ, Hamperl S, et al. (2020) qDRIP: a method to quantitatively assess RNA-DNA hybrid formation genome-wide. Nucleic Acids Research
Bai G, Kermi C, Stoy H, et al. (2020) HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis. Molecular Cell
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