Nicholas J. Hargus, Ph.D.
Affiliations: | 2011 | University of Virginia, Charlottesville, VA |
Area:
Neuroscience BiologyGoogle:
"Nicholas Hargus"Mean distance: 53433
Parents
Sign in to add mentor| Edward Bertram | grad student | 2011 | UVA | |
| (Mechanisms of Increased Neuronal Activity of Entorhinal Cortex Neurons in Temporal Lobe Epilespy.) | ||||
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Publications
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| Nigam A, Hargus NJ, Barker BS, et al. (2019) Inhibition of T-Type calcium channels in mEC layer II stellate neurons reduces neuronal hyperexcitability associated with epilepsy. Epilepsy Research. 154: 132-138 |
| Barker BS, Nigam A, Ottolini M, et al. (2017) Pro-excitatory alterations in sodium channel activity facilitate subiculum neuron hyperexcitability in temporal lobe epilepsy. Neurobiology of Disease |
| Hargus NJ, Thayer SA. (2013) Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17908-20 |
| Hargus NJ, Nigam A, Bertram EH, et al. (2013) Evidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesis. Journal of Neurophysiology. 110: 1144-57 |
| Hargus NJ, Jennings C, Perez-Reyes E, et al. (2012) Enhanced actions of adenosine in medial entorhinal cortex layer II stellate neurons in temporal lobe epilepsy are mediated via A(1)-receptor activation. Epilepsia. 53: 168-76 |
| Hargus NJ, Merrick EC, Nigam A, et al. (2011) Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons. Neurobiology of Disease. 41: 361-76 |
| Hargus NJ, Bertram EH, Patel MK. (2009) Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons. Brain Research. 1280: 60-8 |
| Jones PJ, Merrick EC, Batts TW, et al. (2009) Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 328: 201-12 |
| Hargus NJ, Patel MK. (2007) Voltage-gated Na+ channels in neuropathic pain. Expert Opinion On Investigational Drugs. 16: 635-46 |
| Jones PJ, Wang Y, Smith MD, et al. (2007) Hydroxyamide analogs of propofol exhibit state-dependent block of sodium channels in hippocampal neurons: implications for anticonvulsant activity. The Journal of Pharmacology and Experimental Therapeutics. 320: 828-36 |