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Nicholas J. Hargus, Ph.D. - Publications

Affiliations: 
2011 University of Virginia, Charlottesville, VA 
Area:
Neuroscience Biology
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nigam A, Hargus NJ, Barker BS, Ottolini M, Hounshell JA, Bertram EH, Perez-Reyes E, Patel MK. Inhibition of T-Type calcium channels in mEC layer II stellate neurons reduces neuronal hyperexcitability associated with epilepsy. Epilepsy Research. 154: 132-138. PMID 31132598 DOI: 10.1016/J.Eplepsyres.2019.05.006  0.69
2017 Barker BS, Nigam A, Ottolini M, Gaykema RP, Hargus NJ, Patel MK. Pro-excitatory alterations in sodium channel activity facilitate subiculum neuron hyperexcitability in temporal lobe epilepsy. Neurobiology of Disease. PMID 28860087 DOI: 10.1016/J.Nbd.2017.08.018  0.729
2013 Hargus NJ, Thayer SA. Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17908-20. PMID 24198379 DOI: 10.1523/Jneurosci.1312-13.2013  0.377
2013 Hargus NJ, Nigam A, Bertram EH, Patel MK. Evidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesis. Journal of Neurophysiology. 110: 1144-57. PMID 23741036 DOI: 10.1152/Jn.00383.2013  0.717
2012 Hargus NJ, Jennings C, Perez-Reyes E, Bertram EH, Patel MK. Enhanced actions of adenosine in medial entorhinal cortex layer II stellate neurons in temporal lobe epilepsy are mediated via A(1)-receptor activation. Epilepsia. 53: 168-76. PMID 22126400 DOI: 10.1111/J.1528-1167.2011.03337.X  0.685
2011 Hargus NJ, Merrick EC, Nigam A, Kalmar CL, Baheti AR, Bertram EH, Patel MK. Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons. Neurobiology of Disease. 41: 361-76. PMID 20946956 DOI: 10.1016/J.Nbd.2010.10.004  0.717
2009 Hargus NJ, Bertram EH, Patel MK. Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons. Brain Research. 1280: 60-8. PMID 19450566 DOI: 10.1016/J.Brainres.2009.05.027  0.635
2009 Jones PJ, Merrick EC, Batts TW, Hargus NJ, Wang Y, Stables JP, Bertram EH, Brown ML, Patel MK. Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 328: 201-12. PMID 18952887 DOI: 10.1124/Jpet.108.144709  0.668
2007 Hargus NJ, Patel MK. Voltage-gated Na+ channels in neuropathic pain. Expert Opinion On Investigational Drugs. 16: 635-46. PMID 17461737 DOI: 10.1517/13543784.16.5.635  0.328
2007 Jones PJ, Wang Y, Smith MD, Hargus NJ, Eidam HS, White HS, Kapur J, Brown ML, Patel MK. Hydroxyamide analogs of propofol exhibit state-dependent block of sodium channels in hippocampal neurons: implications for anticonvulsant activity. The Journal of Pharmacology and Experimental Therapeutics. 320: 828-36. PMID 17090703 DOI: 10.1124/Jpet.106.111542  0.643
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