Robert G. Thorne
Affiliations: | New York University School of Medicine, New York, NY, United States |
Area:
extracellular diffusion & convection, drug deliveryGoogle:
"Robert Thorne"Mean distance: 15.26 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentorWilliam H. Frey II | grad student | UMN | |
Charles Nicholson | post-doc | New York University School of Medicine |
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Publications
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Barker SJ, Thayer MB, Kim C, et al. (2024) Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier. Science Translational Medicine. 16: eadi2245 |
Badaut J, Ghersi-Egea JF, Thorne RG, et al. (2024) Blood-brain borders: a proposal to address limitations of historical blood-brain barrier terminology. Fluids and Barriers of the Cns. 21: 3 |
Chew KS, Wells RC, Moshkforoush A, et al. (2023) Author Correction: CD98hc is a target for brain delivery of biotherapeutics. Nature Communications. 14: 5516 |
Chew KS, Wells RC, Moshkforoush A, et al. (2023) CD98hc is a target for brain delivery of biotherapeutics. Nature Communications. 14: 5053 |
van Lengerich B, Zhan L, Xia D, et al. (2023) A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models. Nature Neuroscience |
Arguello A, Mahon CS, Calvert MEK, et al. (2022) Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme. The Journal of Experimental Medicine. 219 |
Nehra G, Andrews S, Rettig J, et al. (2021) Intranasal administration of the chemotherapeutic perillyl alcohol results in selective delivery to the cerebrospinal fluid in rats. Scientific Reports. 11: 6351 |
Bourasset F, Auvity S, Thorne RG, et al. (2021) Brain Distribution of Drugs: Brain Morphology, Delivery Routes, and Species Differences. Handbook of Experimental Pharmacology |
Kariolis MS, Wells RC, Getz JA, et al. (2020) Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys. Science Translational Medicine. 12 |
Ullman JC, Arguello A, Getz JA, et al. (2020) Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice. Science Translational Medicine. 12 |