Robert G. Thorne

Affiliations: 
New York University School of Medicine, New York, NY, United States 
Area:
extracellular diffusion & convection, drug delivery
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"Robert Thorne"
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Publications

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Barker SJ, Thayer MB, Kim C, et al. (2024) Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier. Science Translational Medicine. 16: eadi2245
Badaut J, Ghersi-Egea JF, Thorne RG, et al. (2024) Blood-brain borders: a proposal to address limitations of historical blood-brain barrier terminology. Fluids and Barriers of the Cns. 21: 3
Chew KS, Wells RC, Moshkforoush A, et al. (2023) Author Correction: CD98hc is a target for brain delivery of biotherapeutics. Nature Communications. 14: 5516
Chew KS, Wells RC, Moshkforoush A, et al. (2023) CD98hc is a target for brain delivery of biotherapeutics. Nature Communications. 14: 5053
van Lengerich B, Zhan L, Xia D, et al. (2023) A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models. Nature Neuroscience
Arguello A, Mahon CS, Calvert MEK, et al. (2022) Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme. The Journal of Experimental Medicine. 219
Nehra G, Andrews S, Rettig J, et al. (2021) Intranasal administration of the chemotherapeutic perillyl alcohol results in selective delivery to the cerebrospinal fluid in rats. Scientific Reports. 11: 6351
Bourasset F, Auvity S, Thorne RG, et al. (2021) Brain Distribution of Drugs: Brain Morphology, Delivery Routes, and Species Differences. Handbook of Experimental Pharmacology
Kariolis MS, Wells RC, Getz JA, et al. (2020) Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys. Science Translational Medicine. 12
Ullman JC, Arguello A, Getz JA, et al. (2020) Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice. Science Translational Medicine. 12
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