John Mumm, Ph.D.
Affiliations: | 2005 | The University of Texas Graduate School of Biomedical Sciences at Houston |
Area:
ImmunologyGoogle:
"John Mumm"Parents
Sign in to add mentor| Elizabeth A. Grimm | grad student | 2005 | The University of Texas Graduate School of Biomedical Sciences at Houston | |
| (IL -24; a glycosylated dimeric cytokine affecting monocytes and cytotoxic to melanoma cells.) | ||||
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Publications
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| Wang Y, Mumm JB, Herbst R, et al. (2017) IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression. Journal of Immunology (Baltimore, Md. : 1950) |
| Chan IH, Wu V, Bilardello M, et al. (2016) PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO. Oncoimmunology. 5: e1197458 |
| Naing A, Papadopoulos KP, Autio KA, et al. (2016) Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology |
| Papadopoulos KP, Naing A, Infante JR, et al. (2016) Anti-tumor activity of PEGylated human IL-10 (AM0010) in patients with pancreatic or colorectal cancer. Journal of Clinical Oncology. 34: 3082-3082 |
| Naing A, Papadopoulos KP, Infante JR, et al. (2016) Clinical activity and safety of pegylated human IL-10 (AM0010) in combination with anti-PD1. Journal of Clinical Oncology. 34: 3018-3018 |
| Naing A, Infante JR, Papadopoulos KP, et al. (2016) Abstract PR08: Antitumor activity and immune correlates of PEGylated human IL-10 (AM0010) alone or in combination with anti-PD-1 Cancer Immunology Research. 4 |
| Chan IH, Wu V, McCauley S, et al. (2015) IL-10: Expanding the Immune Oncology Horizon. Receptors & Clinical Investigation. 2 |
| Chan IH, Wu V, Bilardello M, et al. (2015) The Potentiation of IFN-γ and Induction of Cytotoxic Proteins by Pegylated IL-10 in Human CD8 T Cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research |
| Chan IH, Jain R, Tessmer MS, et al. (2014) Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells. Mucosal Immunology. 7: 842-56 |
| Mumm JB, Oft M. (2013) Pegylated IL-10 induces cancer immunity: the surprising role of IL-10 as a potent inducer of IFN-γ-mediated CD8(+) T cell cytotoxicity. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 623-31 |