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John Mumm, Ph.D. - Publications

Affiliations: 
2005 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Immunology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Wang Y, Mumm JB, Herbst R, Kolbeck R, Wang Y. IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression. Journal of Immunology (Baltimore, Md. : 1950). PMID 28939759 DOI: 10.4049/jimmunol.1700152  0.496
2016 Chan IH, Wu V, Bilardello M, Jorgenson B, Bal H, McCauley S, Van Vlasselaer P, Mumm JB. PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO. Oncoimmunology. 5: e1197458. PMID 27622052 DOI: 10.1080/2162402X.2016.1197458  0.436
2016 Naing A, Papadopoulos KP, Autio KA, Ott PA, Patel MR, Wong DJ, Falchook GS, Pant S, Whiteside M, Rasco DR, Mumm JB, Chan IH, Bendell JC, Bauer TM, Colen RR, et al. Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27528724 DOI: 10.1200/JCO.2016.68.1106  0.5
2016 Papadopoulos KP, Naing A, Infante JR, Autio KA, Ott PA, Wong DJL, Falchook GS, Patel MR, Pant S, Whiteside M, Mumm JB, Chan IH, Bendell JC, Rasco DW, Shih KC, et al. Anti-tumor activity of PEGylated human IL-10 (AM0010) in patients with pancreatic or colorectal cancer. Journal of Clinical Oncology. 34: 3082-3082. DOI: 10.1200/JCO.2016.34.15_SUPPL.3082  0.455
2016 Naing A, Papadopoulos KP, Infante JR, Wong DJL, Autio KA, Ott PA, Falchook GS, Patel MR, Pant S, Patnaik A, Mumm JB, Whiteside M, Chan IH, Bendell JC, Bauer TM, et al. Clinical activity and safety of pegylated human IL-10 (AM0010) in combination with anti-PD1. Journal of Clinical Oncology. 34: 3018-3018. DOI: 10.1200/JCO.2016.34.15_SUPPL.3018  0.32
2016 Naing A, Infante JR, Papadopoulos KP, Wong DJ, Autio KA, Falchook GS, Patel M, Pant S, Patnaik A, Whiteside M, Bendell JC, Mumm J, Chan IH, Brown GL, VanVlasselaer P, et al. Abstract PR08: Antitumor activity and immune correlates of PEGylated human IL-10 (AM0010) alone or in combination with anti-PD-1 Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-Pr08  0.51
2015 Chan IH, Wu V, McCauley S, Grimm EA, Mumm JB. IL-10: Expanding the Immune Oncology Horizon. Receptors & Clinical Investigation. 2. PMID 26661378 DOI: 10.14800/Rci.1041  0.595
2015 Chan IH, Wu V, Bilardello M, Mar E, Oft M, Van Vlasselaer P, Mumm JB. The Potentiation of IFN-γ and Induction of Cytotoxic Proteins by Pegylated IL-10 in Human CD8 T Cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. PMID 26309093 DOI: 10.1089/jir.2014.0221  0.502
2014 Chan IH, Jain R, Tessmer MS, Gorman D, Mangadu R, Sathe M, Vives F, Moon C, Penaflor E, Turner S, Ayanoglu G, Chang C, Basham B, Mumm JB, Pierce RH, et al. Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells. Mucosal Immunology. 7: 842-56. PMID 24280935 DOI: 10.1038/Mi.2013.101  0.561
2013 Mumm JB, Oft M. Pegylated IL-10 induces cancer immunity: the surprising role of IL-10 as a potent inducer of IFN-γ-mediated CD8(+) T cell cytotoxicity. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 623-31. PMID 23666891 DOI: 10.1002/bies.201300004  0.57
2012 Emmerich J, Mumm JB, Oft M. Autochthonous T cells to the rescue: IL-10 directly activates tumor-resident CD8(+) T cells. Oncoimmunology. 1: 1637-1639. PMID 23264920 DOI: 10.4161/onci.21683  0.492
2012 Mumm JB, Emmerich J, Oft M. Killing from within. Oncoimmunology. 1: 1598-1600. PMID 23264906 DOI: 10.4161/onci.21423  0.579
2012 Emmerich J, Mumm JB, Chan IH, LaFace D, Truong H, McClanahan T, Gorman DM, Oft M. IL-10 directly activates and expands tumor-resident CD8(+) T cells without de novo infiltration from secondary lymphoid organs. Cancer Research. 72: 3570-81. PMID 22581824 DOI: 10.1158/0008-5472.CAN-12-0721  0.542
2011 Mumm JB, Emmerich J, Zhang X, Chan I, Wu L, Mauze S, Blaisdell S, Basham B, Dai J, Grein J, Sheppard C, Hong K, Cutler C, Turner S, LaFace D, et al. IL-10 elicits IFNγ-dependent tumor immune surveillance. Cancer Cell. 20: 781-96. PMID 22172723 DOI: 10.1016/j.ccr.2011.11.003  0.537
2011 Mumm JB, Oft M. Subversion and coercion: the art of redirecting tumor immune surveillance. Current Topics in Microbiology and Immunology. 344: 25-39. PMID 20490777 DOI: 10.1007/82_2010_47  0.325
2010 Rankin AL, Mumm JB, Murphy E, Turner S, Yu N, McClanahan TK, Bourne PA, Pierce RH, Kastelein R, Pflanz S. IL-33 induces IL-13-dependent cutaneous fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 184: 1526-35. PMID 20042577 DOI: 10.4049/jimmunol.0903306  0.506
2008 Mumm JB, Oft M. Cytokine-based transformation of immune surveillance into tumor-promoting inflammation. Oncogene. 27: 5913-9. PMID 18836472 DOI: 10.1038/onc.2008.275  0.343
2008 Ekmekcioglu S, Mumm JB, Udtha M, Chada S, Grimm EA. Killing of human melanoma cells induced by activation of class I interferon-regulated signaling pathways via MDA-7/IL-24. Cytokine. 43: 34-44. PMID 18511292 DOI: 10.1016/J.Cyto.2008.04.010  0.661
2006 Mumm JB, Ekmekcioglu S, Poindexter NJ, Chada S, Grimm EA. Soluble human MDA-7/IL-24: characterization of the molecular form(s) inhibiting tumor growth and stimulating monocytes. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 877-86. PMID 17238830 DOI: 10.1089/Jir.2006.26.877  0.666
2005 Chada S, Bocangel D, Ramesh R, Grimm EA, Mumm JB, Mhashilkar AM, Zheng M. mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 724-33. PMID 15851011 DOI: 10.1016/J.Ymthe.2004.12.021  0.66
2004 Chada S, Mhashilkar AM, Ramesh R, Mumm JB, Sutton RB, Bocangel D, Zheng M, Grimm EA, Ekmekcioglu S. Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 1085-95. PMID 15564140 DOI: 10.1016/J.Ymthe.2004.08.020  0.675
2004 Chada S, Sutton RB, Ekmekcioglu S, Ellerhorst J, Mumm JB, Leitner WW, Yang HY, Sahin AA, Hunt KK, Fuson KL, Poìndexter N, Roth JA, Ramesh R, Grimm EA, Mhashilkar AM. MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family. International Immunopharmacology. 4: 649-67. PMID 15120650 DOI: 10.1016/J.Intimp.2004.01.017  0.699
2003 Ramesh R, Mhashilkar AM, Tanaka F, Saito Y, Branch CD, Sieger K, Mumm JB, Stewart AL, Boquoi A, Dumoutier L, Grimm EA, Renauld JC, Kotenko S, Chada S, Boquio A. Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor. Cancer Research. 63: 5105-13. PMID 12941841  0.668
2003 Ekmekcioglu S, Ellerhorst JA, Mumm JB, Zheng M, Broemeling L, Prieto VG, Stewart AL, Mhashilkar AM, Chada S, Grimm EA. Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells. Molecular Cancer Therapeutics. 2: 9-17. PMID 12533668  0.539
2002 Stewart AL, Mhashilkar AM, Yang XH, Ekmekcioglu S, Saito Y, Sieger K, Schrock R, Onishi E, Swanson X, Mumm JB, Zumstein L, Watson GJ, Snary D, Roth JA, Grimm EA, et al. PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells. Molecular Medicine (Cambridge, Mass.). 8: 451-61. PMID 12435856  0.547
2002 Caudell EG, Mumm JB, Poindexter N, Ekmekcioglu S, Mhashilkar AM, Yang XH, Retter MW, Hill P, Chada S, Grimm EA. The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24. Journal of Immunology (Baltimore, Md. : 1950). 168: 6041-6. PMID 12055212 DOI: 10.4049/Jimmunol.168.12.6041  0.657
2002 Stewart AL, Mhashilkar AM, Yang XH, Ekmekcioglu S, Saito Y, Sieger K, Schrock R, Onishi E, Swanson X, Mumm JB, Zumstein L, Watson GJ, Snary D, Roth JA, Grimm EA, et al. PI3K Blockade by Ad-PTEN Inhibits Invasion and Induces Apoptosis in Radial Growth Phase and Metastatic Melanoma Cells Molecular Medicine. 8: 451-461. DOI: 10.1007/Bf03402025  0.57
2001 He XS, Rehermann B, Boisvert J, Mumm J, Maecker HT, Roederer M, Wright TL, Maino VC, Davis MM, Greenberg HB. Direct functional analysis of epitope-specific CD8+ T cells in peripheral blood. Viral Immunology. 14: 59-69. PMID 11270597 DOI: 10.1089/08828240151061400  0.359
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