Mark S. Sevecka, Ph.D.

Affiliations: 
2009 Harvard University, Cambridge, MA, United States 
Area:
Bioinformatics Biology, Molecular Biology
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"Mark Sevecka"

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Gavin MacBeth grad student 2009 Harvard
 (Development of lysate microarray technology for quantitative analysis of EGFR signaling.)
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Publications

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Hass H, Masson K, Wohlgemuth S, et al. (2018) Abstract 1312: Predicting ligand-dependent tumors from multi-dimensional signaling features Cancer Research. 78: 1312-1312
Hass H, Masson K, Wohlgemuth S, et al. (2017) Predicting ligand-dependent tumors from multi-dimensional signaling features. Npj Systems Biology and Applications. 3: 27
Kearns JD, Bukhalid R, Sevecka M, et al. (2015) Enhanced Targeting of the EGFR Network with MM-151, an Oligoclonal Anti-EGFR Antibody Therapeutic. Molecular Cancer Therapeutics. 14: 1625-36
Wagner JP, Wolf-Yadlin A, Sevecka M, et al. (2013) Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks. Science Signaling. 6: ra58
Wainszelbaum MJ, Sevecka MS, Burenkova O, et al. (2013) Abstract 5464: In-vitro studies of MM-121/SAR 256212, an anti-ErbB-3 antibody, in combination with erlotinib in EGFR-wild-type NSCLC. Cancer Research. 73: 5464-5464
Luckert K, Gujral TS, Chan M, et al. (2012) A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins. Science Signaling. 5: pl1
Sevecka M, Wolf-Yadlin A, MacBeath G. (2011) Lysate microarrays enable high-throughput, quantitative investigations of cellular signaling. Molecular & Cellular Proteomics : McP. 10: M110.005363
Wolf-Yadlin A, Sevecka M, MacBeath G. (2009) Dissecting protein function and signaling using protein microarrays. Current Opinion in Chemical Biology. 13: 398-405
Gordus A, Krall JA, Beyer EM, et al. (2009) Linear combinations of docking affinities explain quantitative differences in RTK signaling. Molecular Systems Biology. 5: 235
Sevecka M, MacBeath G. (2006) State-based discovery: a multidimensional screen for small-molecule modulators of EGF signaling. Nature Methods. 3: 825-31
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