Peter Kirwan, B.A., M.Phil
Affiliations: | University of Cambridge, Cambridge, England, United Kingdom |
Area:
Cortical circuitry, pluripotent stem cellsGoogle:
"Peter Kirwan"Mean distance: 16.84 (cluster 11) | S | N | B | C | P |
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Publications
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| Sonoyama T, Stadler LKJ, Zhu M, et al. (2020) Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities. Scientific Reports. 10: 9028 |
| Razolli D, de Araújo T, Sant'Ana M, et al. (2019) POMC processing in the hypothalamus is directly regulated by saturated fat - implications for the development of obesity. Neuroendocrinology |
| Kirwan P, Kay RG, Brouwers B, et al. (2018) Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis. Molecular Metabolism |
| Heeley N, Kirwan P, Darwish T, et al. (2018) Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights. Molecular Metabolism |
| Kirwan P, Jura M, Merkle FT. (2017) Generation and Characterization of Functional Human Hypothalamic Neurons. Current Protocols in Neuroscience. 81: 3.33.1-3.33.24 |
| Kirwan P, Turner-Bridger B, Peter M, et al. (2015) Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro. Development (Cambridge, England). 142: 3178-87 |
| Moore S, Evans LD, Andersson T, et al. (2015) APP metabolism regulates tau proteostasis in human cerebral cortex neurons. Cell Reports. 11: 689-96 |
| Ali FR, Cheng K, Kirwan P, et al. (2014) The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro. Development (Cambridge, England). 141: 2216-24 |
| Shi Y, Kirwan P, Livesey FJ. (2012) Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nature Protocols. 7: 1836-46 |
| Shi Y, Kirwan P, Smith J, et al. (2012) A human stem cell model of early Alzheimer's disease pathology in Down syndrome. Science Translational Medicine. 4: 124ra29 |