Amandine Grimm, Ph.D.

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2015 Strasbourg, Strasbourg, Grand Est, France 
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Guy A. Mensah-Nyagan grad student 2015 Strasbourg
 (Mitochondria, neurosteroids and biological rhythms : implications in health and disease states)
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Publications

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Fairley LH, Lai KO, Grimm A, et al. (2024) The mitochondrial translocator protein (TSPO) in Alzheimer's disease: Therapeutic and immunomodulatory functions. Biochimie
Fairley LH, Grimm A, Herff SA, et al. (2024) Translocator protein (TSPO) ligands attenuate mitophagy deficits in the SH-SY5Y cellular model of Alzheimer's disease via the autophagy adaptor P62. Biochimie
Szabo L, Grimm A, García-León JA, et al. (2023) Genetically Engineered Triple -Mutant Human-Induced Pluripotent Stem Cells (N279K, P301L, and E10+16 Mutations) Exhibit Impairments in Mitochondrial Bioenergetics and Dynamics. Cells. 12
Szabo L, Cummins N, Paganetti P, et al. (2023) ER-mitochondria contacts and cholesterol metabolism are disrupted by disease-associated tau protein. Embo Reports. e57499
Fairley LH, Lejri I, Grimm A, et al. (2023) Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein. International Journal of Molecular Sciences. 24
Brilkova M, Nigri M, Kumar HS, et al. (2022) Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice. Cell Reports. 40: 111433
Grimm A. (2021) Impairments in Brain Bioenergetics in Aging and Tau Pathology: A Chicken and Egg Situation? Cells. 10
Szabo L, Eckert A, Grimm A. (2020) Insights into Disease-Associated Tau Impact on Mitochondria. International Journal of Molecular Sciences. 21
Lejri I, Grimm A, Eckert A. (2019) Ginkgo biloba extract increases neurite outgrowth and activates the Akt/mTOR pathway. Plos One. 14: e0225761
Grimm A, Lejri I, Hallé F, et al. (2019) Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies. Journal of Neuroendocrinology. e12796
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