Year |
Citation |
Score |
2024 |
Fairley LH, Grimm A, Herff SA, Eckert A. Translocator protein (TSPO) ligands attenuate mitophagy deficits in the SH-SY5Y cellular model of Alzheimer's disease via the autophagy adaptor P62. Biochimie. PMID 38280505 DOI: 10.1016/j.biochi.2024.01.012 |
0.435 |
|
2023 |
Szabo L, Grimm A, García-León JA, Verfaillie CM, Eckert A. Genetically Engineered Triple -Mutant Human-Induced Pluripotent Stem Cells (N279K, P301L, and E10+16 Mutations) Exhibit Impairments in Mitochondrial Bioenergetics and Dynamics. Cells. 12. PMID 37408218 DOI: 10.3390/cells12101385 |
0.385 |
|
2023 |
Szabo L, Cummins N, Paganetti P, Odermatt A, Papassotiropoulos A, Karch C, Götz J, Eckert A, Grimm A. ER-mitochondria contacts and cholesterol metabolism are disrupted by disease-associated tau protein. Embo Reports. e57499. PMID 37401859 DOI: 10.15252/embr.202357499 |
0.382 |
|
2023 |
Fairley LH, Lejri I, Grimm A, Eckert A. Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein. International Journal of Molecular Sciences. 24. PMID 36982371 DOI: 10.3390/ijms24065297 |
0.459 |
|
2022 |
Brilkova M, Nigri M, Kumar HS, Moore J, Mantovani M, Keller C, Grimm A, Eckert A, Shcherbakov D, Akbergenov R, Seebeck P, Krämer SD, Wolfer DP, Gent TC, Böttger EC. Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice. Cell Reports. 40: 111433. PMID 36170830 DOI: 10.1016/j.celrep.2022.111433 |
0.41 |
|
2021 |
Grimm A. Impairments in Brain Bioenergetics in Aging and Tau Pathology: A Chicken and Egg Situation? Cells. 10. PMID 34685510 DOI: 10.3390/cells10102531 |
0.413 |
|
2020 |
Szabo L, Eckert A, Grimm A. Insights into Disease-Associated Tau Impact on Mitochondria. International Journal of Molecular Sciences. 21. PMID 32882957 DOI: 10.3390/Ijms21176344 |
0.519 |
|
2019 |
Lejri I, Grimm A, Eckert A. Ginkgo biloba extract increases neurite outgrowth and activates the Akt/mTOR pathway. Plos One. 14: e0225761. PMID 31790465 DOI: 10.1371/Journal.Pone.0225761 |
0.346 |
|
2019 |
Grimm A, Lejri I, Hallé F, Schmitt M, Götz J, Bihel F, Eckert A. Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies. Journal of Neuroendocrinology. e12796. PMID 31536662 DOI: 10.1111/Jne.12796 |
0.462 |
|
2019 |
Lejri I, Grimm A, Hallé F, Abarghaz M, Klein C, Maitre M, Schmitt M, Bourguignon JJ, Mensah-Nyagan AG, Bihel F, Eckert A. TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis. Journal of Alzheimer's Disease : Jad. PMID 31256132 DOI: 10.3233/Jad-190127 |
0.447 |
|
2019 |
Lejri I, Agapouda A, Grimm A, Eckert A. Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Related Disorders: From Molecular Mechanisms to Clinical Evidence. Oxidative Medicine and Cellular Longevity. 2019: 9695412. PMID 31214285 DOI: 10.1155/2019/9695412 |
0.456 |
|
2019 |
Poirier Y, Grimm A, Schmitt K, Eckert A. Link between the unfolded protein response and dysregulation of mitochondrial bioenergetics in Alzheimer's disease. Cellular and Molecular Life Sciences : Cmls. PMID 30683981 DOI: 10.1007/S00018-019-03009-4 |
0.572 |
|
2018 |
Grimm A, Cummins N, Götz J. Local Oxidative Damage in the Soma and Dendrites Quarantines Neuronal Mitochondria at the Site of Insult. Iscience. 6: 114-127. PMID 30240605 DOI: 10.1016/J.Isci.2018.07.015 |
0.316 |
|
2018 |
Lejri I, Grimm A, Eckert A. Mitochondria, Estrogen and Female Brain Aging. Frontiers in Aging Neuroscience. 10: 124. PMID 29755342 DOI: 10.3389/Fnagi.2018.00124 |
0.419 |
|
2018 |
Schmitt K, Grimm A, Dallmann R, Oettinghaus B, Restelli LM, Witzig M, Ishihara N, Mihara K, Ripperger JA, Albrecht U, Frank S, Brown SA, Eckert A. Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics. Cell Metabolism. PMID 29478834 DOI: 10.1016/J.Cmet.2018.01.011 |
0.366 |
|
2017 |
Grimm A, Eckert A. Brain aging and neurodegeneration: from a mitochondrial point of view. Journal of Neurochemistry. PMID 28397282 DOI: 10.1111/Jnc.14037 |
0.393 |
|
2017 |
Schmitt K, Grimm A, Eckert A. Amyloid-β-Induced Changes in Molecular Clock Properties and Cellular Bioenergetics. Frontiers in Neuroscience. 11: 124. PMID 28367108 DOI: 10.3389/Fnins.2017.00124 |
0.504 |
|
2016 |
Wilkaniec A, Schmitt K, Grimm A, Strosznajder JB, Eckert A. Alzheimer's amyloid-β peptide disturbs P2X7 receptor-mediated circadian oscillations of intracellular calcium. Folia Neuropathologica. 54: 360-368. PMID 28139817 DOI: 10.5114/Fn.2016.64813 |
0.448 |
|
2016 |
Lejri I, Grimm A, Miesch M, Geoffroy P, Eckert A, Mensah-Nyagan AG. Allopregnanolone and its analog BR 297 rescue neuronal cells from oxidative stress-induced death through bioenergetic improvement. Biochimica Et Biophysica Acta. PMID 27979708 DOI: 10.1016/J.Bbadis.2016.12.007 |
0.41 |
|
2016 |
Grimm A, Mensah-Nyagan AG, Eckert A. Alzheimer, mitochondria and gender. Neuroscience and Biobehavioral Reviews. PMID 27139022 DOI: 10.1016/J.Neubiorev.2016.04.012 |
0.504 |
|
2016 |
Grimm A, Friedland K, Eckert A. Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer's disease. Biogerontology. 17: 281-96. PMID 26468143 DOI: 10.1007/S10522-015-9618-4 |
0.486 |
|
2016 |
Grimm A, Schmitt K, Eckert A. Advanced mitochondrial respiration assay for evaluation of mitochondrial dysfunction in Alzheimer’s disease Methods in Molecular Biology. 1303: 171-183. PMID 26235066 DOI: 10.1007/978-1-4939-2627-5_9 |
0.569 |
|
2016 |
Grimm A, Biliouris EE, Lang UE, Götz J, Mensah-Nyagan AG, Eckert A. Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein. Cellular and Molecular Life Sciences : Cmls. 73: 201-15. PMID 26198711 DOI: 10.1007/S00018-015-1988-X |
0.639 |
|
2016 |
Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, Späni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L. Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer’s disease Molecular Psychiatry. DOI: 10.1038/Mp.2016.112 |
0.539 |
|
2015 |
Oettinghaus B, Schulz JM, Restelli LM, Licci M, Savoia C, Schmidt A, Schmitt K, Grimm A, Morè L, Hench J, Tolnay M, Eckert A, D'Adamo P, Franken P, Ishihara N, et al. Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons. Cell Death and Differentiation. PMID 25909888 DOI: 10.1038/Cdd.2015.39 |
0.348 |
|
2015 |
Eckert A, Grimm A, Mensah-Nyagan G. Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein Alzheimers & Dementia. 11: 368. DOI: 10.1016/J.Jalz.2015.06.276 |
0.391 |
|
2014 |
Grimm A, Schmitt K, Lang UE, Mensah-Nyagan AG, Eckert A. Improvement of neuronal bioenergetics by neurosteroids: Implications for age-related neurodegenerative disorders Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1842: 2427-2438. PMID 25281013 DOI: 10.1016/J.Bbadis.2014.09.013 |
0.43 |
|
2014 |
Eckert A, Nisbet R, Grimm A, Götz J. March separate, strike together--role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease. Biochimica Et Biophysica Acta. 1842: 1258-66. PMID 24051203 DOI: 10.1016/J.Bbadis.2013.08.013 |
0.556 |
|
2012 |
Grimm A, Lim YA, Mensah-Nyagan AG, Götz J, Eckert A. Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship. Molecular Neurobiology. 46: 151-60. PMID 22678467 DOI: 10.1007/S12035-012-8281-X |
0.532 |
|
2012 |
Schmitt K, Grimm A, Kazmierczak A, Strosznajder JB, Götz J, Eckert A. Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio. Antioxidants & Redox Signaling. 16: 1456-66. PMID 22117646 DOI: 10.1089/Ars.2011.4400 |
0.616 |
|
2011 |
Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Götz J. Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol Plos One. 6. PMID 22174920 DOI: 10.1371/Journal.Pone.0028887 |
0.581 |
|
2011 |
Grimm A, Lim Y, Rhein V, Mensah-Nyagan AG, Götz J, Eckert A. Effects of amyloid-beta and human amylin on mitochondrial function and estradiol production Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1115 |
0.372 |
|
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