Florian Lesage

IPMC CNRS & University of Nice (France) 
"Florian Lesage"
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Royal P, Andres-Bilbe A, Ávalos Prado P, et al. (2019) Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK. Neuron. 101: 232-245.e6
Soussia IB, Choveau FS, Blin S, et al. (2018) Antagonistic Effect of a Cytoplasmic Domain on the Basal Activity of Polymodal Potassium Channels. Frontiers in Molecular Neuroscience. 11: 301
Bobak N, Feliciangeli S, Chen CC, et al. (2017) Recombinant tandem of pore-domains in a Weakly Inward rectifying K(+) channel 2 (TWIK2) forms active lysosomal channels. Scientific Reports. 7: 649
Christensen AH, Chatelain FC, Huttner IG, et al. (2016) The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size. Journal of Molecular and Cellular Cardiology
Ronjat M, Feng W, Dardevet L, et al. (2016) In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptide. Proceedings of the National Academy of Sciences of the United States of America
Blin S, Ben Soussia I, Kim EJ, et al. (2016) Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties. Proceedings of the National Academy of Sciences of the United States of America
Feliciangeli S, Chatelain FC, Bichet D, et al. (2015) The family of K2P channels: salient structural and functional properties. The Journal of Physiology. 593: 2587-603
Bichet D, Blin S, Feliciangeli S, et al. (2015) Silent but not dumb: how cellular trafficking and pore gating modulate expression of TWIK1 and THIK2. Pflugers Archiv : European Journal of Physiology. 467: 1121-31
Pereira V, Busserolles J, Christin M, et al. (2014) Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception. Pain. 155: 2534-44
Comoglio Y, Levitz J, Kienzler MA, et al. (2014) Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid. Proceedings of the National Academy of Sciences of the United States of America. 111: 13547-52
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