Carlos Cruchaga

Washington University School of Medicine, St. Louis, MO, United States 
Alzheimer's, genetics, genomics, quantitative traits, WES, WGS, proteomics
"Carlos Cruchaga"
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Doering S, McCullough A, Gordon BA, et al. (2024) Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging. Ebiomedicine. 103: 105080
Meeker KL, Luckett PH, Barthélemy NR, et al. (2024) Comparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer's disease. Brain Communications. 6: fcae081
Cruchaga C, Ali M, Shen Y, et al. (2024) Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer's disease. Research Square
Joseph-Mathurin N, Feldman RL, Lu R, et al. (2024) Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Wang Q, Schindler SE, Chen G, et al. (2024) Investigating White Matter Neuroinflammation in Alzheimer Disease Using Diffusion-Based Neuroinflammation Imaging. Neurology. 102: e208013
Shen Y, Ali M, Timsina J, et al. (2024) Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways. Medrxiv : the Preprint Server For Health Sciences
Vance JM, Farrer LA, Huang Y, et al. (2024) Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease. Annals of Neurology
Wang L, Nykänen NP, Western D, et al. (2024) Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease. Molecular Neurodegeneration. 19: 1
Gunasekaran TI, Reyes-Dumeyer D, Faber KM, et al. (2023) Identification of Rare Damaging Missense and Loss of Function Variants in GWAS Loci Using Genome Sequencing Data from Two Cohorts of Familial Late-Onset Alzheimer's Disease. Medrxiv : the Preprint Server For Health Sciences
Millar PR, Gordon BA, Wisch JK, et al. (2023) Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease. Molecular Neurodegeneration. 18: 98
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