Stephen J. Ralph

Affiliations: 
School of Medical Sciences Griffith University 
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"Stephen Ralph"
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Ralph S, Mani S, Swargiary G, et al. (2023) Therapeutic Targeting of Mitochondrial Plasticity and Redox Control to Overcome Cancer Chemoresistance. Antioxidants & Redox Signaling
Mani S, Swargiary G, Ralph SJ. (2021) Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy. Mitochondrion. 62: 50-73
Clark AM, Magawa C, Pliego-Zamora A, et al. (2021) Tea tree oil extract causes mitochondrial superoxide production and apoptosis as an anticancer agent, promoting tumor infiltrating neutrophils cytotoxic for breast cancer to induce tumor regression. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 140: 111790
Ralph SJ, Nozuhur S, ALHulais RA, et al. (2019) Repurposing drugs as pro-oxidant redox modifiers to eliminate cancer stem cells and improve the treatment of advanced stage cancers. Medicinal Research Reviews
ALHulais RA, Ralph SJ. (2019) Cancer stem cells, stemness markers and selected drug targeting: metastatic colorectal cancer and cyclooxygenase-2/prostaglandin E2 connection to WNT as a model system Journal of Cancer Metastasis and Treatment. 2019
Pritchard R, Rodríguez-Enríquez S, Pacheco-Velázquez SC, et al. (2018) Celecoxib inhibits mitochondrial O consumption, promoting ROS dependent death of murine and human metastatic cancer cells via the apoptotic signalling pathway. Biochemical Pharmacology
Ralph SJ, Nozuhur S, Moreno-Sánchez R, et al. (2018) NSAID celecoxib: a potent mitochondrial pro-oxidant cytotoxic agent sensitizing metastatic cancers and cancer stem cells to chemotherapy Journal of Cancer Metastasis and Treatment. 4: 49
Cutler SJ, Doecke JD, Ghazawi I, et al. (2017) Novel STAT binding elements mediate IL-6 regulation of MMP-1 and MMP-3. Scientific Reports. 7: 8526
Yu X, Scott SA, Pritchard R, et al. (2015) Redox state influence on human galectin-1 function. Biochimie
Low P, Clark AM, Chou TC, et al. (2015) Immunomodulatory activity of Melaleuca alternifolia concentrate (MAC): inhibition of LPS-induced NF-κB activation and cytokine production in myeloid cell lines. International Immunopharmacology. 26: 257-64
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