David Brooks
Affiliations: | 2003-2008 | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
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Publications
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| Guo M, Abd-Rabbo D, Bertol BC, et al. (2023) Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control. Cell Reports. 42: 113047 |
| Guo M, Abd-Rabbo D, Bertol B, et al. (2023) Molecular, metabolic and functional CD4 T cell paralysis impedes tumor control. Biorxiv : the Preprint Server For Biology |
| Lukhele S, Rabbo DA, Guo M, et al. (2022) The transcription factor IRF2 drives interferon-mediated CD8 T cell exhaustion to restrict anti-tumor immunity. Immunity |
| Snell LM, Xu W, Abd-Rabbo D, et al. (2021) Dynamic CD4 T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection. Nature Immunology |
| Brooks DG, Tishon A, Oldstone MBA, et al. (2021) Prevention of CD8 T Cell Deletion during Chronic Viral Infection. Viruses. 13 |
| Loo Yau H, Bell E, Ettayebi I, et al. (2021) DNA hypomethylating agents increase activation and cytolytic activity of CD8 T cells. Molecular Cell |
| Xu W, Snell LM, Guo M, et al. (2021) Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection. Immunity |
| Macleod BL, Elsaesser HJ, Snell LM, et al. (2020) A network of immune and microbial modifications underlies viral persistence in the gastrointestinal tract. The Journal of Experimental Medicine. 217 |
| Elsaesser HJ, Mohtashami M, Osokine I, et al. (2020) Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection. Proceedings of the National Academy of Sciences of the United States of America |
| Lukhele S, Boukhaled GM, Brooks DG. (2019) Type I interferon signaling, regulation and gene stimulation in chronic virus infection. Seminars in Immunology |